LPAL13_130011900

mitochondrial processing peptidase alpha subunit, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_146937 OG7: OG7_0001887 73 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 73 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_200031200 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LPAL13_000005500 ⚠
Peptidase family M3, putative
— OG7
LPAL13_350053900 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LPAL13_180013800 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LPAL13_260026800 ⚠
kynureninase, putative
— OG7
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_270034000 ⚠
peptidyl dipeptidase, putative
— OG7
LPAL13_200039000 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LPAL13_290015500 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LPAL13_150016400 ⚠
protein kinase, putative
— OG7
LPAL13_320024400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340035500 ⚠
Hydroxyneurosporene synthase (CrtC), putative
— OG7
LPAL13_200020100 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_330006500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_110006300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350048100 ⚠
S-adenosylhomocysteine hydrolase
— OG7
LPAL13_350020100 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LPAL13_040008700 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LPAL13_350029800 ⚠
developmentally regulated GTP-binding protein
— OG7
LPAL13_280027500 ⚠
protein kinase, putative
— OG7
LPAL13_290022600 ⚠
serine/threonine protein kinase, putative
— OG7
LPAL13_210006600 ⚠
serine/threonine-protein kinase-like protein
— OG7
LPAL13_350015000 ⚠
SNF1-related protein kinases, putative
— OG7
LPAL13_320019700 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LPAL13_070014900 ⚠
serine/threonine kinase, putative
— OG7
LPAL13_330025100 ⚠
protein kinase, putative
— OG7
LPAL13_000039300 ⚠
serine/threonine kinase-like protein, putativ
— OG7
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— OG7
LPAL13_070006000 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LPAL13_260010400 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LPAL13_000032500 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LPAL13_350030700 ⚠
tyrosine aminotransferase
— OG7
LPAL13_300037200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_170007500 ⚠
cystathionine beta-synthase
— OG7
LPAL13_130008500 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LPAL13_040011100 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LPAL13_300028600 ⚠
Hsp70 protein, putative
— OG7
LPAL13_340027500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_330031900 ⚠
udp-glc 4'-epimerase, putative
— OG7
LPAL13_350074100 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_180014300 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat, pu
— OG7
LPAL13_300028500 ⚠
heat-shock protein hsp70, putative
— OG7
LPAL13_300028800 ⚠
Hsp70 protein, putative
— OG7
LPAL13_300029300 ⚠
hypothetical protein
— OG7
LPAL13_200045000 ⚠
Alpha/beta hydrolase family, putative
— OG7
LPAL13_320048300 ⚠
cAMP response protein, putative
— OG7
LPAL13_300028700 ⚠
heat-shock protein hsp70, putative
— OG7
LPAL13_310038100 ⚠
phosphoglycan beta 1,3 galactosyltransferase
— OG7
LPAL13_010010300 ⚠
mitochondrial processing peptide beta subunit
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.