LPAL13_200039000

Programmed cell death protein 2, C-terminal putative domain containing protein, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_136955 OG7: OG7_0004545 77 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 77 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_070006000 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LPAL13_230014200 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LPAL13_310024900 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LPAL13_340035400 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LPAL13_200017000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_300023600 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LPAL13_270015500 ⚠
WD40 repeats, putative
— OG7
LPAL13_280027600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280025800 ⚠
replication factor A, 51kDa subunit, putative
— OG7
LPAL13_000009600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_330039800 ⚠
tyrosyl-DNA phosphodiesterase 1
— OG7
LPAL13_330023800 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_340027500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_260010400 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_110006300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_030010000 ⚠
kinase-like protein
— OG7
LPAL13_150016100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_180014300 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat, pu
— OG7
LPAL13_350020100 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LPAL13_240019500 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_320024400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_130008500 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LPAL13_300037200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_040011100 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LPAL13_290015500 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LPAL13_330006500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_340031100 ⚠
ankyrin repeat protein, putative
— OG7
LPAL13_180013400 ⚠
5-oxoprolinase, putative
— OG7
LPAL13_040018800 ⚠
tRNA nucleotidyltransferase, putative
— OG7
LPAL13_260025100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300010700 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LPAL13_220013600 ⚠
Beta-lactamase superfamily domain containing
— OG7
LPAL13_220013700 ⚠
Beta-lactamase superfamily domain containing
— OG7
LPAL13_300039000 ⚠
DNA ligase I, putative
— OG7
LPAL13_260025200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310025500 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LPAL13_340035500 ⚠
Hydroxyneurosporene synthase (CrtC), putative
— OG7
LPAL13_110010800 ⚠
anion-transporting ATPase-like protein
— OG7
LPAL13_330035200 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_210008300 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_130011900 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_350029800 ⚠
developmentally regulated GTP-binding protein
— OG7
LPAL13_340059600 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LPAL13_180007100 ⚠
RNA-binding protein 29, putative
— OG7
LPAL13_100011400 ⚠
zinc binding dehydrogenase-like protein
— OG7
LPAL13_100011500 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LPAL13_080007900 ⚠
Isochorismatase family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.