LPAL13_230014200

ubiquitin-activating enzyme E1, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100444 OG7: OG7_0003530 173 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 173 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_200044400 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_350053000 ⚠
ubiquitin protein ligase, putative
— OG7
LPAL13_140014000 ⚠
glutathione synthetase, putative
— Both
LPAL13_300006900 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LPAL13_230013700 ⚠
Galactose oxidase, central domain containing
— Both
LPAL13_340027900 ⚠
hypothetical protein, conserved
— Both
LPAL13_030011800 ⚠
Ubiquitin-like domain containing protein, put
— Both
LPAL13_200056400 ⚠
tubulin-tyrosine ligase, putative
— Both
LPAL13_340027500 ⚠
hypothetical protein, conserved
— Both
LPAL13_210011600 ⚠
nucleotide-binding protein, putative
— Both
LPAL13_280032700 ⚠
MRP protein-like protein
— OG6
LPAL13_260009100 ⚠
nucleotide binding protein-like protein
— Both
LPAL13_200045900 ⚠
hypothetical protein, conserved
— Both
LPAL13_200054100 ⚠
hypothetical protein, conserved
— Both
LPAL13_160007400 ⚠
Met-10+ like-protein, putative
— Both
LPAL13_000014700 ⚠
casein kinase II, alpha chain, putative
— OG6
LPAL13_330008100 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LPAL13_130010900 ⚠
protein kinase, putative
— Both
LPAL13_210015700 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LPAL13_220013700 ⚠
Beta-lactamase superfamily domain containing
— Both
LPAL13_220013600 ⚠
Beta-lactamase superfamily domain containing
— Both
LPAL13_250027700 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
LPAL13_340012200 ⚠
proteasome activator protein pa26, putative
— Both
LPAL13_030011600 ⚠
TatD related DNase, putative
— Both
LPAL13_000024500 ⚠
hydrogenase, putative
— Both
LPAL13_070013200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_100011500 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_000018100 ⚠
Mitochondrial glycoprotein, putative
— OG7
LPAL13_310033600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_230008700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_110006600 ⚠
chromatin binding protein, putative
— OG7
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_320029200 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LPAL13_050012400 ⚠
Mitochondrial glycoprotein, putative
— OG7
LPAL13_000009600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_320016900 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LPAL13_260012000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_350006800 ⚠
elongation factor 2
— OG7
LPAL13_200017000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_160008200 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LPAL13_330007100 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LPAL13_160015700 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LPAL13_150019500 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LPAL13_280025300 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_270014000 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LPAL13_320022200 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.