LPAL13_320016900

HECT-domain (ubiquitin-transferase), putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102181 OG7: OG7_0002947 160 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 160 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_260012000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_170005600 ⚠
Ring finger domain containing protein, putati
— OG7
LPAL13_350037500 ⚠
predicted zinc finger protein
— OG7
LPAL13_210019600 ⚠
Ring finger domain containing protein, putati
— OG7
LPAL13_320029200 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LPAL13_340035400 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LPAL13_230014200 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LPAL13_250023800 ⚠
elongation factor 2-like protein
— OG7
LPAL13_350006800 ⚠
elongation factor 2
— OG7
LPAL13_330015800 ⚠
Protein prenyltransferase alpha subunit repea
— OG7
LPAL13_300026600 ⚠
Leucine rich repeat, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_050011800 ⚠
Vta1 like, putative
— OG7
LPAL13_160009500 ⚠
aspartate carbamoyltransferase, putative
— OG7
LPAL13_300035100 ⚠
homoserine kinase, putative
— OG7
LPAL13_330007100 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LPAL13_200031100 ⚠
zinc carboxypeptidase, putative
— OG7
LPAL13_350049600 ⚠
zinc carboxypeptidase, putative
— OG7
LPAL13_080007900 ⚠
Isochorismatase family, putative
— OG7
LPAL13_080008100 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LPAL13_120005600 ⚠
ribonuclease mar1
— OG7
LPAL13_080008000 ⚠
Isochorismatase family, putative
— OG7
LPAL13_050009200 ⚠
GTPase, putative
— OG7
LPAL13_050007000 ⚠
50S ribosome-binding GTPase, putative
— OG7
LPAL13_340058600 ⚠
GTP-binding protein, putative
— OG7
LPAL13_260018500 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LPAL13_330033000 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_230008700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310026700 ⚠
Fungal tRNA ligase phosphodiesterase domain c
— OG7
LPAL13_000032500 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LPAL13_230013700 ⚠
Galactose oxidase, central domain containing
— OG7
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_310033600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_110006600 ⚠
chromatin binding protein, putative
— OG7
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_340050700 ⚠
sm-f snRNP core complex protein, putative
— OG7
LPAL13_060015300 ⚠
TLD, putative
— OG7
LPAL13_000024500 ⚠
hydrogenase, putative
— OG7
LPAL13_260009100 ⚠
nucleotide binding protein-like protein
— OG7
LPAL13_210011600 ⚠
nucleotide-binding protein, putative
— OG7
LPAL13_260010900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340037500 ⚠
Peroxin 19
— OG7
LPAL13_090014900 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
LPAL13_100017600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LPAL13_300010700 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LPAL13_350026400 ⚠
TLD, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.