LPAL13_000032500

3-mercaptopyruvate sulfurtransferase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100692 OG7: OG7_0004631 132 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 132 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_270015500
WD40 repeats, putative
— Both
LPAL13_260012000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_190020300 ⚠
mitogen activated protein kinase 4, putative
— OG6
LPAL13_180019700
gamma-glutamylcysteine synthetase, putative
— Both
LPAL13_300011600
nitrate reductase, putative
— OG6
LPAL13_140017000
enolase
— Both
LPAL13_350030700
tyrosine aminotransferase
— Both
LPAL13_340050800 ⚠
CS domain containing protein, putative
— Both
LPAL13_200005800 ⚠
CS domain containing protein, putative
— Both
LPAL13_350078100
2,3-bisphosphoglycerate-independent phosphogl
— Both
LPAL13_330035200 ⚠
mitochondrial processing peptidase alpha subu
— Both
LPAL13_000014700
casein kinase II, alpha chain, putative
— OG6
LPAL13_030011600
TatD related DNase, putative
— Both
LPAL13_000024500
hydrogenase, putative
— Both
LPAL13_130011900 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_210008300 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_050009200 ⚠
GTPase, putative
— OG7
LPAL13_340058600 ⚠
GTP-binding protein, putative
— OG7
LPAL13_260018500 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LPAL13_330033000 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_000018100 ⚠
Mitochondrial glycoprotein, putative
— OG7
LPAL13_230008700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310033600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_110006600 ⚠
chromatin binding protein, putative
— OG7
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_300026700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_180008600 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LPAL13_320029200 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_050012400 ⚠
Mitochondrial glycoprotein, putative
— OG7
LPAL13_000009600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340055500 ⚠
tubulin tyrosine ligase, putative
— OG7
LPAL13_320016900 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LPAL13_350033700 ⚠
cyclin-e binding protein 1-like protein
— OG7
LPAL13_200043400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LPAL13_350049600 ⚠
zinc carboxypeptidase, putative
— OG7
LPAL13_320037200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_090014900 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
LPAL13_350049800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_170007400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_100017600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LPAL13_260025100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_290030500 ⚠
START domain containing protein, putative
— OG7
LPAL13_150016400 ⚠
protein kinase, putative
— OG7
LPAL13_200031200 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LPAL13_320048300 ⚠
cAMP response protein, putative
— OG7
LPAL13_080008000 ⚠
Isochorismatase family, putative
— OG7
LPAL13_260012100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_120005600 ⚠
ribonuclease mar1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.