LPAL13_200043400

HECT-domain (ubiquitin-transferase), putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_158358 OG7: OG7_0002947 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_340054400 ⚠
breast cancer carboxy-terminal domain contain
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_310033600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_110006600 ⚠
chromatin binding protein, putative
— OG7
LPAL13_340050700 ⚠
sm-f snRNP core complex protein, putative
— OG7
LPAL13_260012000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_320016700 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LPAL13_260005100 ⚠
Lsm7p protein, putative
— OG7
LPAL13_000034700 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_200022200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_350049800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_170007400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_350033700 ⚠
cyclin-e binding protein 1-like protein
— OG7
LPAL13_260012100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_160008200 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LPAL13_000018400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270016400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_200044400 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_280027600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280025800 ⚠
replication factor A, 51kDa subunit, putative
— OG7
LPAL13_200047400 ⚠
sjogren s syndrome nuclear autoantigen 1, put
— OG7
LPAL13_220011100 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LPAL13_230027800 ⚠
Surp module, putative
— OG7
LPAL13_150015400 ⚠
glutamate dehydrogenase
— OG7
LPAL13_200029900 ⚠
methyltransferase-like protein
— OG7
LPAL13_210014400 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— OG7
LPAL13_180009400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280019100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000039200 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LPAL13_070006000 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LPAL13_110012800 ⚠
PUB domain containing protein, putative
— OG7
LPAL13_090017600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LPAL13_180014800 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LPAL13_090014900 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
LPAL13_100017600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LPAL13_300038200 ⚠
calmodulin-related protein, putative
— OG7
LPAL13_080009200 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_200057900 ⚠
cyclophilin 15, putative
— OG7
LPAL13_260009000 ⚠
pseudouridylate synthase-like protein
— OG7
LPAL13_000022400 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LPAL13_000021400 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LPAL13_300010700 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LPAL13_000024500 ⚠
hydrogenase, putative
— OG7
LPAL13_260009100 ⚠
nucleotide binding protein-like protein
— OG7
LPAL13_320016400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200006800 ⚠
tRNA pseudouridine synthase, putative
— OG7
LPAL13_090016500 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.