LPAL13_330035200

mitochondrial processing peptidase alpha subunit, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102381 OG7: OG7_0001887 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_280027800 ⚠
NADH dehydrogenase subunit NB6M, putative
— OG7
LPAL13_330006500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_040008700 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— OG7
LPAL13_270015500 ⚠
WD40 repeats, putative
— OG7
LPAL13_340059600 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LPAL13_340031100 ⚠
ankyrin repeat protein, putative
— OG7
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_320048300 ⚠
cAMP response protein, putative
— OG7
LPAL13_180014300 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat, pu
— OG7
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_070005600 ⚠
cytochrome c1, heme protein, mitochondrial pr
— OG7
LPAL13_340018500 ⚠
mitochondrial processing peptidase, beta subu
— OG7
LPAL13_350029800 ⚠
developmentally regulated GTP-binding protein
— Both
LPAL13_070006000 ⚠
metallo-peptidase, Clan ME, Family M16C
— Both
LPAL13_350044800 ⚠
cysteine synthase
— OG6
LPAL13_260010400 ⚠
Protein of unknown function (DUF525), putativ
— Both
LPAL13_000032500 ⚠
3-mercaptopyruvate sulfurtransferase
— Both
LPAL13_350030700 ⚠
tyrosine aminotransferase
— Both
LPAL13_170007500 ⚠
cystathionine beta-synthase
— Both
LPAL13_000039300 ⚠
serine/threonine kinase-like protein, putativ
— OG7
LPAL13_280027500 ⚠
protein kinase, putative
— OG7
LPAL13_290022600 ⚠
serine/threonine protein kinase, putative
— OG7
LPAL13_210006600 ⚠
serine/threonine-protein kinase-like protein
— OG7
LPAL13_350015000 ⚠
SNF1-related protein kinases, putative
— OG7
LPAL13_240012100 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LPAL13_320019700 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LPAL13_070014900 ⚠
serine/threonine kinase, putative
— OG7
LPAL13_090018500 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LPAL13_330025100 ⚠
protein kinase, putative
— OG7
LPAL13_300011600
nitrate reductase, putative
— OG6
LPAL13_000053700 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LPAL13_300037200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_040011100 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LPAL13_350053900 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LPAL13_180013800 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LPAL13_200039000 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LPAL13_150016400 ⚠
protein kinase, putative
— OG7
LPAL13_200031200 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LPAL13_340027500 ⚠
hypothetical protein, conserved
— Both
LPAL13_130006800 ⚠
protein kinase A regulatory subunit, putative
— Both
LPAL13_240006600 ⚠
hypothetical protein, conserved
— Both
LPAL13_280008700 ⚠
rrp44p homologue, putative
— Both
LPAL13_210015700 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LPAL13_240019500 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_260021000 ⚠
thimet oligopeptidase, putative
— Both
LPAL13_040018800 ⚠
tRNA nucleotidyltransferase, putative
— Both
LPAL13_330020700 ⚠
mitogen activated protein kinase, putative
— OG6
LPAL13_180013400 ⚠
5-oxoprolinase, putative
— Both
LPAL13_250027700 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.