LPAL13_350030700

tyrosine aminotransferase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101502 OG7: OG7_0001321 63 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 63 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_270019700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_330034400 ⚠
carboxypeptidase, putative
— Both
LPAL13_130006000 ⚠
carboxypeptidase, putative
— Both
LPAL13_340019300 ⚠
choline/ethanolamine kinase, putative
— Both
LPAL13_260007800 ⚠
aminopeptidase-like protein
— Both
LPAL13_140006600 ⚠
hypothetical protein
— Both
LPAL13_070006000
metallo-peptidase, Clan ME, Family M16C
— Both
LPAL13_350074100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_260006400 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LPAL13_330013000 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_270021400 ⚠
choline kinase
— OG7
LPAL13_270015500
WD40 repeats, putative
— OG7
LPAL13_290026300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_350079400 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LPAL13_340040300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_170020000
otubain cysteine peptidase, Clan CA, family C
— Both
LPAL13_350080500 ⚠
DNA-binding protein, putative
— OG7
LPAL13_320006000 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_120014300 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LPAL13_350042400 ⚠
Bromodomain, putative
— OG7
LPAL13_290024900 ⚠
aminopeptidase, putative
— OG7
LPAL13_340030600 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LPAL13_250023200 ⚠
dullard-like phosphatase domain containing pr
— OG7
LPAL13_130011900 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_210008300 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_320048300 ⚠
cAMP response protein, putative
— OG7
LPAL13_200031200 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LPAL13_150016400 ⚠
protein kinase, putative
— OG7
LPAL13_340018500 ⚠
mitochondrial processing peptidase, beta subu
— OG7
LPAL13_350053900 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LPAL13_280023400
phosphonopyruvate decarboxylase-like protein
— Both
LPAL13_260026800
kynureninase, putative
— Both
LPAL13_350044800 ⚠
cysteine synthase
— OG6
LPAL13_340005400
2-oxoisovalerate dehydrogenase beta subunit,
— Both
LPAL13_300011600
nitrate reductase, putative
— OG6
LPAL13_010010300 ⚠
mitochondrial processing peptide beta subunit
— Both
LPAL13_350038000 ⚠
bromodomain factor 2 protein, putative
— Both
LPAL13_260021000 ⚠
thimet oligopeptidase, putative
— Both
LPAL13_000005600 ⚠
Peptidase family M3, putative
— Both
LPAL13_270034000 ⚠
peptidyl dipeptidase, putative
— Both
LPAL13_000005500 ⚠
Peptidase family M3, putative
— Both
LPAL13_060014300
dihydrofolate reductase-thymidylate synthase
— Both
LPAL13_130006800 ⚠
protein kinase A regulatory subunit, putative
— Both
LPAL13_200025100
twinfilin, putative
— Both
LPAL13_000032500
3-mercaptopyruvate sulfurtransferase
— Both
LPAL13_350020100
The ARF-like 2 binding protein BART, putative
— Both
LPAL13_170007500 ⚠
cystathionine beta-synthase
— Both
LPAL13_330035200 ⚠
mitochondrial processing peptidase alpha subu
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.