LPAL13_350044800

cysteine synthase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100154 OG7: OG7_0002171 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_230011600 ⚠
AMP-binding enzyme/AMP-binding enzyme C-termi
— Both
LPAL13_230011500 ⚠
acetyl-CoA synthetase, putative
— Both
LPAL13_000018900 ⚠
AMP-binding enzyme/AMP-binding enzyme C-termi
— Both
LPAL13_270026700 ⚠
trypanothione synthetase, putative
— Both
LPAL13_260012800 ⚠
aspartate--ammonia ligase, putative
— Both
LPAL13_000016500 ⚠
AMP-binding enzyme, putative
— Both
LPAL13_220015100 ⚠
ribonucleoside-diphosphate reductase small ch
— OG6
LPAL13_240013500 ⚠
malic enzyme, putative
— Both
LPAL13_200054700 ⚠
cytidine triphosphate synthase, putative
— OG6
LPAL13_270028600 ⚠
branched-chain amino acid aminotransferase, p
— OG6
LPAL13_300018000 ⚠
pyridoxal kinase, putative
— OG6
LPAL13_040011700 ⚠
spermidine synthase
— OG6
LPAL13_270028800 ⚠
ribonucleoside-diphosphate reductase small ch
— OG6
LPAL13_280037000 ⚠
cytosolic malate dehydrogenase
— OG6
LPAL13_290031300 ⚠
inosine-adenosine-guanosine-nucleoside hydrol
— OG6
LPAL13_240028100 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— OG6
LPAL13_330035200 ⚠
mitochondrial processing peptidase alpha subu
— OG6
LPAL13_280035900 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_280036500 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_280018900 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_260017100 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_280036000 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_350065500 ⚠
aminopeptidase P1, putative
— OG7
LPAL13_330037500 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LPAL13_300041500 ⚠
Protein of unknown function (DUF3808)/Tetratr
— OG6
LPAL13_260013400 ⚠
heat shock 70 protein-like protein
— OG7
LPAL13_010010200 ⚠
HSP70-like protein
— OG7
LPAL13_340053700 ⚠
Hsp70 protein, putative
— OG7
LPAL13_180016300 ⚠
heat shock protein 110, putative
— OG7
LPAL13_000007500 ⚠
paraflagellar rod protein 1D, putative
— OG7
LPAL13_330037600 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LPAL13_230010400 ⚠
trypanothione synthetase, putative
— OG7
LPAL13_230015100 ⚠
3-ketoacyl-CoA thiolase, putative
— OG6
LPAL13_250027300 ⚠
hypothetical protein
— OG7
LPAL13_250027100 ⚠
glutathionylspermidine synthase, putative
— OG7
LPAL13_250027200 ⚠
hypothetical protein
— OG7
LPAL13_090013900 ⚠
Uncharacterised protein family (UPF0160), put
— Both
LPAL13_140008600 ⚠
threonine synthase, putative
— OG6
LPAL13_350078100 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG6
LPAL13_290024900 ⚠
aminopeptidase, putative
— OG6
LPAL13_350081400 ⚠
elks delta-like protein
— OG6
LPAL13_350048100 ⚠
S-adenosylhomocysteine hydrolase
— OG6
LPAL13_250027700 ⚠
metallo-peptidase, Clan MG, Family M24
— OG6
LPAL13_130006800 ⚠
protein kinase A regulatory subunit, putative
— OG6
LPAL13_330020700 ⚠
mitogen activated protein kinase, putative
— OG6
LPAL13_330031900 ⚠
udp-glc 4'-epimerase, putative
— OG6
LPAL13_170007500 ⚠
cystathionine beta-synthase
— OG6
LPAL13_230020000 ⚠
hypothetical protein, conserved
— OG6
LPAL13_340046600 ⚠
kinetoplastid kinetochore protein 3, putative
— OG6
LPAL13_250013700 ⚠
protein phosphatase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.