LPAL13_240028100

3-hydroxy-3-methylglutaryl-CoA synthase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101064 OG7: OG7_0006553 79 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 79 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_300029800
Leucyl/phenylalanyl-tRNA protein transferase,
— OG7
LPAL13_210006600 ⚠
serine/threonine-protein kinase-like protein
— OG7
LPAL13_350015000 ⚠
SNF1-related protein kinases, putative
— OG7
LPAL13_280022700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LPAL13_340008600 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LPAL13_330025100 ⚠
protein kinase, putative
— OG7
LPAL13_010011900 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LPAL13_000053700 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LPAL13_120014300 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LPAL13_260007800 ⚠
aminopeptidase-like protein
— OG7
LPAL13_290022600 ⚠
serine/threonine protein kinase, putative
— OG7
LPAL13_340026300 ⚠
adenine aminohydrolase
— OG7
LPAL13_150007800 ⚠
sterol carrier protein, putative
— OG7
LPAL13_200054700
cytidine triphosphate synthase, putative
— Both
LPAL13_150015900 ⚠
AhpC/TSA family/C-terminal domain of 1-Cys pe
— Both
LPAL13_230005300 ⚠
peroxidoxin
— Both
LPAL13_230015100 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LPAL13_150015700 ⚠
tryparedoxin peroxidase
— Both
LPAL13_000009500 ⚠
fumarate hydratase, putative
— Both
LPAL13_240008300 ⚠
fumarate hydratase, putative
— Both
LPAL13_290026300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_250023800 ⚠
elongation factor 2-like protein
— OG7
LPAL13_320029200 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LPAL13_250023200 ⚠
dullard-like phosphatase domain containing pr
— OG7
LPAL13_280025000 ⚠
NOL1/NOP2/sun family, putative
— OG7
LPAL13_340030600 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LPAL13_320006000 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_320031800 ⚠
NOL1/NOP2/sun family, putative
— OG7
LPAL13_340040300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_350079400 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LPAL13_320037400
nucleoside diphosphate kinase b
— Both
LPAL13_290022400 ⚠
NOL1/NOP2/sun family, putative
— OG7
LPAL13_310006900 ⚠
nucleolar protein, putative
— OG7
LPAL13_270021400 ⚠
choline kinase
— OG7
LPAL13_340006900 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_260006400 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LPAL13_330012800 ⚠
hypothetical protein
— OG7
LPAL13_340027700 ⚠
protein kinase, putative
— OG7
LPAL13_190005400 ⚠
serine/threonine protein kinase, putative
— OG7
LPAL13_280027500 ⚠
protein kinase, putative
— OG7
LPAL13_000039300 ⚠
serine/threonine kinase-like protein, putativ
— Both
LPAL13_280015000
ribonucleoside-diphosphate reductase large ch
— Both
LPAL13_310005000
5-methyltetrahydropteroyltriglutamate-homocys
— Both
LPAL13_250024200
KIF-1 binding protein C terminal, putative
— Both
LPAL13_300037800
hypothetical protein, conserved
— Both
LPAL13_330013000 ⚠
NLI interacting factor-like phosphatase, puta
— Both
LPAL13_330028900
hypothetical protein, conserved
— Both
LPAL13_260012800
aspartate--ammonia ligase, putative
— Both
LPAL13_070014900 ⚠
serine/threonine kinase, putative
— Both
LPAL13_210021700 ⚠
RNA helicase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.