LPAL13_280015000

ribonucleoside-diphosphate reductase large chain, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100448 OG7: OG7_0004229 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_340006900 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_050012800
methylthioadenosine phosphorylase, putative
— Both
LPAL13_230015100 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LPAL13_340038200
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LPAL13_250005100
n-terminal acetyltransferase complex ard1 sub
— Both
LPAL13_300010700
N-acetyltransferase B complex (NatB) non cata
— Both
LPAL13_100008100
isocitrate dehydrogenase [NADP], mitochondria
— Both
LPAL13_050011300
Sperm-tail PG-rich repeat, putative
— Both
LPAL13_330028900
hypothetical protein, conserved
— Both
LPAL13_330013000 ⚠
NLI interacting factor-like phosphatase, puta
— Both
LPAL13_300037800
hypothetical protein, conserved
— Both
LPAL13_310005000
5-methyltetrahydropteroyltriglutamate-homocys
— Both
LPAL13_320024400
hypothetical protein, conserved
— Both
LPAL13_350059000 ⚠
translation initiation factor 2 subunit, puta
— Both
LPAL13_330015700
PSP1 C-terminal conserved region containing p
— Both
LPAL13_350057400
paraflagellar rod component, putative
— Both
LPAL13_290024500
Leucine-rich repeat, putative
— Both
LPAL13_110010800
anion-transporting ATPase-like protein
— Both
LPAL13_240024300 ⚠
calcium/calmodulin-dependent protein kinase,
— Both
LPAL13_100014100 ⚠
hypothetical protein, conserved
— Both
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— Both
LPAL13_280008700 ⚠
rrp44p homologue, putative
— OG7
LPAL13_040008700 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LPAL13_340026300 ⚠
adenine aminohydrolase
— OG7
LPAL13_300029800
Leucyl/phenylalanyl-tRNA protein transferase,
— OG7
LPAL13_330012800 ⚠
hypothetical protein
— OG7
LPAL13_260006400 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LPAL13_030010800
hypothetical protein, conserved
— OG7
LPAL13_150007800 ⚠
sterol carrier protein, putative
— OG7
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LPAL13_180014400 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LPAL13_290008400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_300012600 ⚠
nuclear movement protein, putative
— OG7
LPAL13_290011700 ⚠
heat shock protein 90, putative
— OG7
LPAL13_130010200 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_110010200 ⚠
aminopeptidase, putative
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_300013100 ⚠
heat shock protein grpe
— OG7
LPAL13_170017300 ⚠
NOL1/NOP2/sun family, putative
— OG7
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_330008200 ⚠
heat shock protein 83-17
— OG7
LPAL13_140019600 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LPAL13_290026300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_350079400 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LPAL13_340040300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_320006000 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_340030600 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LPAL13_250023200 ⚠
dullard-like phosphatase domain containing pr
— OG7
LPAL13_300040300 ⚠
serine/threonine-protein kinase, putative
— OG7
LPAL13_320022200 ⚠
Putative GTPase activating protein for Arf, p
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.