LPAL13_040011700

spermidine synthase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100634 OG7: OG7_0003460 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_000052600 ⚠
glycosomal malate dehydrogenase
— OG7
LPAL13_000028700 ⚠
malate dehydrogenase, putative
— OG7
LPAL13_000028500 ⚠
malate dehydrogenase, putative
— OG7
LPAL13_000028600 ⚠
malate dehydrogenase
— Both
LPAL13_200005000 ⚠
mitochondrial malate dehydrogenase
— Both
LPAL13_000037000
ribose 5-phosphate isomerase, putative
— Both
LPAL13_010011900 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LPAL13_010006000 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LPAL13_350078100
2,3-bisphosphoglycerate-independent phosphogl
— Both
LPAL13_220018600 ⚠
ser/thr protein phosphatase, putative
— OG7
LPAL13_350044800 ⚠
cysteine synthase
— OG6
LPAL13_170007500 ⚠
cystathionine beta-synthase
— Both
LPAL13_200020100
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
LPAL13_140008600
threonine synthase, putative
— Both
LPAL13_220015100 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LPAL13_270028800 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LPAL13_270028600
branched-chain amino acid aminotransferase, p
— Both
LPAL13_150010200 ⚠
ecotin, putative
— OG7
LPAL13_030007000 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LPAL13_340008600 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LPAL13_130009900 ⚠
Metallopeptidase family M24, putative
— OG7
LPAL13_280022700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LPAL13_150008400 ⚠
ecotin, putative
— OG7
LPAL13_290008100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_250027200 ⚠
hypothetical protein
— OG7
LPAL13_250027100 ⚠
glutathionylspermidine synthase, putative
— OG7
LPAL13_250027300 ⚠
hypothetical protein
— OG7
LPAL13_330037500 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LPAL13_230010400 ⚠
trypanothione synthetase, putative
— OG7
LPAL13_330037600 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LPAL13_350053900 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LPAL13_350077200
y113g7b.23 protein-like protein
— Both
LPAL13_270026700 ⚠
trypanothione synthetase, putative
— Both
LPAL13_320015300
ubiquitin-conjugating enzyme protein, putativ
— Both
LPAL13_260010900
hypothetical protein, conserved
— Both
LPAL13_310030400 ⚠
uridine kinase-like protein
— Both
LPAL13_290031300
inosine-adenosine-guanosine-nucleoside hydrol
— Both
LPAL13_200015000 ⚠
uracil phosphoribosyltransferase, putative
— Both
LPAL13_060011200
deoxyuridine triphosphatase, putative
— Both
LPAL13_280037000
cytosolic malate dehydrogenase
— Both
LPAL13_060011800
protein kinase, putative
— OG6
LPAL13_220010100 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— Both
LPAL13_210021700 ⚠
RNA helicase, putative
— Both
LPAL13_060018000
protein kinase, putative
— OG6
LPAL13_070007100
protein phosphatase 2A, regulatory subunit B,
— Both
LPAL13_150010300 ⚠
ecotin, putative
— Both
LPAL13_010010100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LPAL13_330034200
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
LPAL13_250026500
serine/threonine-protein kinase, putative
— OG6
LPAL13_060016700
deoxyribose-phosphate aldolase, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.