LPAL13_060016700

deoxyribose-phosphate aldolase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102064 OG7: OG7_0007190 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_280020700 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_340005000
pyruvate kinase
— Both
LPAL13_100007000
mitogen-activated protein kinase, putative
— OG6
LPAL13_250024400
succinyl-CoA synthetase alpha subunit, putati
— Both
LPAL13_200041400
phosphomannomutase-like protein
— Both
LPAL13_280030000
hd phosphohydrolase family protein
— Both
LPAL13_320041500
dihydrolipoamide dehydrogenase, putative
— Both
LPAL13_280020600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LPAL13_290017800 ⚠
carnitine/choline acetyltransferase, putative
— Both
LPAL13_350054400
Protein of unknown function (DUF2870), putati
— Both
LPAL13_280020800 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LPAL13_280020500 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_280020400 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_190021500 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LPAL13_280020300 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LPAL13_260027200
nitrilase, putative
— Both
LPAL13_220008100 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LPAL13_010011900 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LPAL13_220018600 ⚠
ser/thr protein phosphatase, putative
— OG7
LPAL13_150010200 ⚠
ecotin, putative
— OG7
LPAL13_340008600 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LPAL13_130009900 ⚠
Metallopeptidase family M24, putative
— OG7
LPAL13_000028500 ⚠
malate dehydrogenase, putative
— OG7
LPAL13_280022700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LPAL13_000028700 ⚠
malate dehydrogenase, putative
— OG7
LPAL13_150008400 ⚠
ecotin, putative
— OG7
LPAL13_290008100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000052600 ⚠
glycosomal malate dehydrogenase
— OG7
LPAL13_350053900 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LPAL13_040011700
spermidine synthase
— Both
LPAL13_210021700 ⚠
RNA helicase, putative
— Both
LPAL13_060018000
protein kinase, putative
— OG6
LPAL13_070007100
protein phosphatase 2A, regulatory subunit B,
— Both
LPAL13_150010300 ⚠
ecotin, putative
— Both
LPAL13_350077200
y113g7b.23 protein-like protein
— Both
LPAL13_330034200
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
LPAL13_200005000 ⚠
mitochondrial malate dehydrogenase
— Both
LPAL13_000028600 ⚠
malate dehydrogenase
— Both
LPAL13_250026500
serine/threonine-protein kinase, putative
— OG6
LPAL13_170010900 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— Both
LPAL13_190009600 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
LPAL13_200063500
hypothetical protein, conserved
— Both
LPAL13_220006200
glutamine amidotransferase, putative
— Both
LPAL13_220010100 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— Both
LPAL13_160011300
transaldolase, putative
— Both
LPAL13_260021000 ⚠
thimet oligopeptidase, putative
— Both
LPAL13_000005600 ⚠
Peptidase family M3, putative
— Both
LPAL13_270034000 ⚠
peptidyl dipeptidase, putative
— Both
LPAL13_000005500 ⚠
Peptidase family M3, putative
— Both
LPAL13_340013000 ⚠
aspartate aminotransferase, putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.