LPAL13_250024400

succinyl-CoA synthetase alpha subunit, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100834 OG7: OG7_0005210 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_350037700
succinyl-CoA ligase [GDP-forming] beta-chain,
— +2 more Both
LPAL13_000024300 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LPAL13_350049000
hs1vu complex proteolytic subunit-like, threo
— Both
LPAL13_200022000
pyroglutamyl-peptidase I (C15 family)
— Both
LPAL13_100007000
mitogen-activated protein kinase, putative
— OG6
LPAL13_280030000
hd phosphohydrolase family protein
— Both
LPAL13_320005800
N-myristoyl transferase, putative
— Both
LPAL13_000037000
ribose 5-phosphate isomerase, putative
— Both
LPAL13_060016700
deoxyribose-phosphate aldolase, putative
— Both
LPAL13_000028500 ⚠
malate dehydrogenase, putative
— OG7
LPAL13_000028700 ⚠
malate dehydrogenase, putative
— OG7
LPAL13_000052600 ⚠
glycosomal malate dehydrogenase
— OG7
LPAL13_130014200 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LPAL13_150007800 ⚠
sterol carrier protein, putative
— OG7
LPAL13_190005200 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LPAL13_270014100 ⚠
reductase, putative
— OG7
LPAL13_320030800 ⚠
cytochrome-b5 reductase, putative
— OG7
LPAL13_200041400
phosphomannomutase-like protein
— Both
LPAL13_320045100 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LPAL13_320045000 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LPAL13_340008100 ⚠
serine palmitoyltransferase, putative
— OG7
LPAL13_200040900 ⚠
serine palmitoyltransferase-like protein
— OG7
LPAL13_190021500 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LPAL13_220008100 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LPAL13_280020800 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LPAL13_280020500 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_280020400 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_280020300 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LPAL13_280020700 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_200058200 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LPAL13_200048000 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LPAL13_220006200
glutamine amidotransferase, putative
— Both
LPAL13_240013500 ⚠
malic enzyme, putative
— Both
LPAL13_240028100
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LPAL13_310030400 ⚠
uridine kinase-like protein
— Both
LPAL13_000049500 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LPAL13_230015100 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LPAL13_200015000 ⚠
uracil phosphoribosyltransferase, putative
— Both
LPAL13_150005400 ⚠
cytochrome-b5 reductase, putative
— Both
LPAL13_000049400 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LPAL13_260006200
adenine phosphoribosyltransferase
— Both
LPAL13_100008100
isocitrate dehydrogenase [NADP], mitochondria
— Both
LPAL13_350054400
Protein of unknown function (DUF2870), putati
— Both
LPAL13_340005000
pyruvate kinase
— Both
LPAL13_320041500
dihydrolipoamide dehydrogenase, putative
— Both
LPAL13_340054100
cyclophilin 40
— OG6
LPAL13_240013400 ⚠
malic enzyme, putative
— Both
LPAL13_200005000 ⚠
mitochondrial malate dehydrogenase
— Both
LPAL13_000028600 ⚠
malate dehydrogenase
— Both
LPAL13_320045200 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.