LPAL13_000028600

malate dehydrogenase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101212 OG7: OG7_0004751 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_040011700 ⚠
spermidine synthase
— Both
LPAL13_060008800 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
LPAL13_190005200 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LPAL13_330037500 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LPAL13_250027300 ⚠
hypothetical protein
— OG7
LPAL13_130014200 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LPAL13_300032200 ⚠
chaperonin HSP60/CNP60, putative
— OG7
LPAL13_250027100 ⚠
glutathionylspermidine synthase, putative
— OG7
LPAL13_250027200 ⚠
hypothetical protein
— OG7
LPAL13_230010400 ⚠
trypanothione synthetase, putative
— OG7
LPAL13_200065800 ⚠
hypothetical protein
— Both
LPAL13_090013200 ⚠
oligopeptidase b
— Both
LPAL13_310017200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LPAL13_200065900 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LPAL13_140014700 ⚠
Sodium/hydrogen exchanger family, putative
— Both
LPAL13_300019600 ⚠
hypothetical protein
— Both
LPAL13_050008100 ⚠
trypanothione reductase
— Both
LPAL13_300019500 ⚠
hypothetical protein
— Both
LPAL13_130009900 ⚠
Metallopeptidase family M24, putative
— OG7
LPAL13_290008100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_150008400 ⚠
ecotin, putative
— OG7
LPAL13_150010200 ⚠
ecotin, putative
— OG7
LPAL13_220018600 ⚠
ser/thr protein phosphatase, putative
— OG7
LPAL13_280022700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LPAL13_340008600 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LPAL13_010011900 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LPAL13_350053900 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LPAL13_270014100 ⚠
reductase, putative
— OG7
LPAL13_350079100 ⚠
prolyl oligopeptidase, putative
— OG7
LPAL13_200038100 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LPAL13_330037600 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LPAL13_340039200 ⚠
Replication factor A protein 3, putative
— OG7
LPAL13_320030800 ⚠
cytochrome-b5 reductase, putative
— OG7
LPAL13_230028900 ⚠
cytochrome c oxidase subunit V, putative
— OG7
LPAL13_300019400 ⚠
Peptidase family M20/M25/M40, putative
— Both
LPAL13_350037700 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LPAL13_150005400 ⚠
cytochrome-b5 reductase, putative
— Both
LPAL13_000039600 ⚠
chaperonin HSP60, mitochondrial precursor
— Both
LPAL13_300018000 ⚠
pyridoxal kinase, putative
— Both
LPAL13_250024400 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LPAL13_240014300 ⚠
triosephosphate isomerase
— Both
LPAL13_000049500 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LPAL13_280037000 ⚠
cytosolic malate dehydrogenase
— Both
LPAL13_290031300 ⚠
inosine-adenosine-guanosine-nucleoside hydrol
— Both
LPAL13_000049400 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LPAL13_300015000 ⚠
conserved hypothetical protein, putative
— Both
LPAL13_290023400 ⚠
conserved hypothetical protein, putative
— Both
LPAL13_150010300 ⚠
ecotin, putative
— Both
LPAL13_060016700 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LPAL13_170010900 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.