LPAL13_200065900

N-acyl-L-amino acid amidohydrolase, putative

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101553 OG7: OG7_0005942 169 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 169 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_110010200 ⚠ aminopeptidase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LPAL13_330034700 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LPAL13_280008700 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_280470.1 OG6 LdBPK_201740.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 +1 more	Both
LPAL13_350066100 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LPAL13_280009900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	Both
LPAL13_040008700 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	OG7
LPAL13_240020600 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_241480.1 OG7 LdBPK_201720.1 ↔ LdBPK_241480.1	Both
LPAL13_300024100 ⚠ calpain-like cysteine peptidase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_302040.1 OG6 LdBPK_201740.1 ↔ LdBPK_302040.1	OG6
LPAL13_300035000 ⚠ tRNA (Guanine-1)-methyltransferase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_303110.1 OG6 LdBPK_201740.1 ↔ LdBPK_303110.1 OG7 LdBPK_201720.1 ↔ LdBPK_303110.1 OG7 LdBPK_201740.1 ↔ LdBPK_303110.1	Both
LPAL13_310017200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LPAL13_200020700 ⚠ EAP30/Vps36 family, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_341570.1 OG6 LdBPK_201740.1 ↔ LdBPK_341570.1 OG7 LdBPK_201720.1 ↔ LdBPK_341570.1 OG7 LdBPK_201740.1 ↔ LdBPK_341570.1	Both
LPAL13_200017100 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_341230.1 OG6 LdBPK_201740.1 ↔ LdBPK_341230.1 OG7 LdBPK_201720.1 ↔ LdBPK_341230.1 OG7 LdBPK_201740.1 ↔ LdBPK_341230.1	Both
LPAL13_340047700 ⚠ elongation factor 1-alpha, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_354220.1 OG6 LdBPK_201740.1 ↔ LdBPK_354220.1 OG7 LdBPK_201720.1 ↔ LdBPK_354220.1 OG7 LdBPK_201740.1 ↔ LdBPK_354220.1	Both
LPAL13_200017200 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_341230.1 OG6 LdBPK_201740.1 ↔ LdBPK_341230.1 OG7 LdBPK_201720.1 ↔ LdBPK_341230.1 OG7 LdBPK_201740.1 ↔ LdBPK_341230.1	Both
LPAL13_340016300 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_201720.1 ↔ LdBPK_241120.1 OG6 LdBPK_201740.1 ↔ LdBPK_241120.1	OG6
LPAL13_350072300 ⚠ flagellum transition zone component, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_366480.1 OG6 LdBPK_201740.1 ↔ LdBPK_366480.1 OG7 LdBPK_201720.1 ↔ LdBPK_366480.1 OG7 LdBPK_201740.1 ↔ LdBPK_366480.1	Both
LPAL13_260009500 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_260460.1 OG6 LdBPK_201740.1 ↔ LdBPK_260460.1 OG7 LdBPK_201720.1 ↔ LdBPK_260460.1 OG7 LdBPK_201740.1 ↔ LdBPK_260460.1	Both
LPAL13_200065800 ⚠ hypothetical protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LPAL13_330020900 ⚠ protein kinase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_331490.1 OG6 LdBPK_201740.1 ↔ LdBPK_331490.1 OG7 LdBPK_201720.1 ↔ LdBPK_331490.1 OG7 LdBPK_201740.1 ↔ LdBPK_331490.1	Both
LPAL13_290023900 ⚠ protein kinase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_292260.1 OG6 LdBPK_201740.1 ↔ LdBPK_292260.1 OG7 LdBPK_201720.1 ↔ LdBPK_292260.1 OG7 LdBPK_201740.1 ↔ LdBPK_292260.1	Both
LPAL13_260016900 ⚠ Leucine Rich Repeat/Leucine rich repeat, puta	—	OG6 LdBPK_201720.1 ↔ LdBPK_261200.1 OG6 LdBPK_201740.1 ↔ LdBPK_261200.1 OG7 LdBPK_201720.1 ↔ LdBPK_261200.1 OG7 LdBPK_201740.1 ↔ LdBPK_261200.1	Both
LPAL13_350036400 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_201720.1 ↔ LdBPK_241120.1 OG6 LdBPK_201740.1 ↔ LdBPK_241120.1	OG6
LPAL13_280028300 ⚠ mitochondrial DEAD box protein, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_282220.1 OG6 LdBPK_201740.1 ↔ LdBPK_282220.1 OG7 LdBPK_201720.1 ↔ LdBPK_282220.1 OG7 LdBPK_201740.1 ↔ LdBPK_282220.1	Both
LPAL13_240016800 ⚠ pre-mRNA splicing factor, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_241120.1 OG6 LdBPK_201740.1 ↔ LdBPK_241120.1	OG6
LPAL13_340024200 ⚠ U3 small nucleolar RNA-associated protein 6,	—	OG6 LdBPK_201720.1 ↔ LdBPK_351980.1 OG6 LdBPK_201740.1 ↔ LdBPK_351980.1 OG7 LdBPK_201720.1 ↔ LdBPK_351980.1 OG7 LdBPK_201740.1 ↔ LdBPK_351980.1	Both
LPAL13_350049700 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_008197 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_008197 ↔ TCSYLVIO_008414	Both
LPAL13_300010100 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	Both
LPAL13_210014900 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	Both
LPAL13_200005000 ⚠ mitochondrial malate dehydrogenase	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LPAL13_000028600 ⚠ malate dehydrogenase	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LPAL13_300013000 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_008414	Both
LPAL13_200067100 ⚠ conserved protein, unknown function	—	OG6 LdBPK_200770.1 ↔ LdBPK_201720.1 OG6 LdBPK_200770.1 ↔ LdBPK_201740.1 OG7 LdBPK_200770.1 ↔ LdBPK_201720.1 OG7 LdBPK_200770.1 ↔ LdBPK_201740.1	Both
LPAL13_120007700 ⚠ ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_201720.1 OG6 LdBPK_120105.1 ↔ LdBPK_201740.1 OG7 LdBPK_120105.1 ↔ LdBPK_201720.1 OG7 LdBPK_120105.1 ↔ LdBPK_201740.1	Both
LPAL13_330016800 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004910 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004910 ↔ TCSYLVIO_008414	Both
LPAL13_290023000 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_201720.1 OG7 LdBPK_130530.1 ↔ LdBPK_201740.1	OG7
LPAL13_170011700 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LPAL13_200028600 ⚠ acyl-CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LPAL13_170011400 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LPAL13_200038100 ⚠ ruvb-like 1 DNA helicase, putative	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008414	OG7
LPAL13_050009200 ⚠ GTPase, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LPAL13_340058600 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LPAL13_260018500 ⚠ guanine nucleotide-binding protein-like prote	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LPAL13_330033000 ⚠ ras-like small GTPases, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LPAL13_030005400 ⚠ Met-10+ like-protein, putative	—	OG7 LdBPK_160320.1 ↔ LdBPK_201720.1 OG7 LdBPK_160320.1 ↔ LdBPK_201740.1	OG7
LPAL13_140019600 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_008414	OG7
LPAL13_030010800 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_008414 ↔ TCSYLVIO_010148	OG7
LPAL13_340035800 ⚠ ATP-dependent RNA helicase, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_282220.1 OG7 LdBPK_201740.1 ↔ LdBPK_282220.1	OG7
LPAL13_200025600 ⚠ asparaginyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	OG7
LPAL13_080005700 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_282220.1 OG7 LdBPK_201740.1 ↔ LdBPK_282220.1	OG7
LPAL13_300012600 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_008414 ↔ TCSYLVIO_010327	OG7

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