LPAL13_130009900

Metallopeptidase family M24, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_146697 OG7: OG7_0006554 80 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 80 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_000052600 ⚠
glycosomal malate dehydrogenase
— OG7
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LPAL13_350082100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_180007200 ⚠
60S ribosomal protein L7, putative
— OG7
LPAL13_200059700 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LPAL13_000005500 ⚠
Peptidase family M3, putative
— OG7
LPAL13_350053900 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LPAL13_270034000 ⚠
peptidyl dipeptidase, putative
— OG7
LPAL13_000005600 ⚠
Peptidase family M3, putative
— OG7
LPAL13_260021000 ⚠
thimet oligopeptidase, putative
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_290008100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270014000 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LPAL13_000028600 ⚠
malate dehydrogenase
— OG7
LPAL13_200005000 ⚠
mitochondrial malate dehydrogenase
— OG7
LPAL13_330034200 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
LPAL13_350077200 ⚠
y113g7b.23 protein-like protein
— OG7
LPAL13_000028700 ⚠
malate dehydrogenase, putative
— OG7
LPAL13_280022700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LPAL13_000028500 ⚠
malate dehydrogenase, putative
— OG7
LPAL13_260018500 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LPAL13_270021800 ⚠
proteasome regulatory non-ATP-ase subunit 3,
— OG7
LPAL13_150008400 ⚠
ecotin, putative
— OG7
LPAL13_150010300 ⚠
ecotin, putative
— OG7
LPAL13_150010200 ⚠
ecotin, putative
— OG7
LPAL13_170010900 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— OG7
LPAL13_220018600 ⚠
ser/thr protein phosphatase, putative
— OG7
LPAL13_330033000 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_320022000 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_190006700 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LPAL13_210021700 ⚠
RNA helicase, putative
— OG7
LPAL13_290015700 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_340058600 ⚠
GTP-binding protein, putative
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_130010000 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_340014500 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LPAL13_100006100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_340056200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_320021000 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LPAL13_050009200 ⚠
GTPase, putative
— OG7
LPAL13_070010700 ⚠
60S ribosomal protein L7a, putative
— Both
LPAL13_350055100 ⚠
PSP1 C-terminal conserved region containing p
— Both
LPAL13_340036900 ⚠
RNA-binding protein, putative
— Both
LPAL13_210023700 ⚠
mitochondrial structure specific endonuclease
— Both
LPAL13_290007800 ⚠
hypothetical protein, conserved
— Both
LPAL13_200013400 ⚠
ribosomal protein L13, putative
— Both
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— Both
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— Both
LPAL13_050007000 ⚠
50S ribosome-binding GTPase, putative
— Both
LPAL13_320005200 ⚠
nuclear segregation protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.