LPAL13_200043100

target of rapamycin kinase (TOR) kinase 3
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_138996 OG7: OG7_0001934 321 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 321 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_000008000 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LPAL13_310032200 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— +1 more Both
LPAL13_330022300 ⚠
Tetratricopeptide repeats, putative
— Both
LPAL13_310032300 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LPAL13_320036300 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LPAL13_350062300 ⚠
glycosyl hydrolase, putative
— Both
LPAL13_240029900 ⚠
cullin-like protein-like protein
— OG7
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_050013400 ⚠
CPSF A subunit region containing protein, put
— OG7
LPAL13_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LPAL13_300041800 ⚠
CPSF-domain protein, putative
— OG7
LPAL13_340048700 ⚠
predicted zinc finger protein
— OG7
LPAL13_210019000 ⚠
adenylate kinase, putative
— OG7
LPAL13_350019500 ⚠
adenylate kinase, putative
— OG7
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310007300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_320039600 ⚠
ribosomal protein L3, putative
— OG7
LPAL13_200031800 ⚠
Ribosomal protein L3, putative
— OG7
LPAL13_210016700 ⚠
60S ribosomal protein L9, putative
— OG7
LPAL13_300038000 ⚠
60S ribosomal protein L9, putative
— OG7
LPAL13_260009700 ⚠
DNA polymerase sigma-like protein
— OG7
LPAL13_350049100 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LPAL13_070012900 ⚠
topoisomerase-related function protein-like p
— OG7
LPAL13_350049200 ⚠
hypothetical protein
— OG7
LPAL13_280021800 ⚠
Cell division control protein 48, putative
— OG7
LPAL13_170015000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LPAL13_130008000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LPAL13_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_150007200 ⚠
60S ribosomal protein L13a, putative
— OG7
LPAL13_200013400 ⚠
ribosomal protein L13, putative
— OG7
LPAL13_350023700 ⚠
neurobeachin/beige protein, putative
— OG7
LPAL13_230026800 ⚠
neutral sphingomyelinase activation associate
— OG7
LPAL13_200007500 ⚠
RNA polymerase ii largest subunit
— OG7
LPAL13_330037000 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LPAL13_310031800 ⚠
RNA polymerase ii largest subunit
— OG7
LPAL13_150011900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000022100 ⚠
tubulin-specific chaperone, putative
— OG7
LPAL13_190016000 ⚠
CAP-Gly domain containing protein, putative
— OG7
LPAL13_170009300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300010400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_060011300 ⚠
60S ribosomal protein L23a, putative
— OG7
LPAL13_200063900 ⚠
zinc-binding phosphatase, putative
— OG7
LPAL13_160017100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_160019400 ⚠
paraflagellar rod protein 1D, putative
— OG7
LPAL13_090017700 ⚠
AAA family ATPase, putative
— OG7
LPAL13_290027100 ⚠
60S ribosomal protein L13, putative
— OG7
LPAL13_300026700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_290027000 ⚠
60S ribosomal protein L13, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.