LPAL13_320036300

CS domain/TPR repeat/Tetratricopeptide repeat, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_105298 OG7: OG7_0010785 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_180015700 ⚠
pre-RNA processing PIH1/Nop17, putative
— Both
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— Both
LPAL13_200059700 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_320021000 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_340049500 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LPAL13_330006400
trans-splicing factor, putative
— Both
LPAL13_250008500
hypothetical protein, conserved
— Both
LPAL13_310032200 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— Both
LPAL13_310015800
hypothetical protein, conserved
— Both
LPAL13_290015600
hypothetical protein, conserved
— Both
LPAL13_040010900 ⚠
Nucleotidyltransferase domain/Cid1 family pol
— Both
LPAL13_150011400
hypothetical protein, conserved
— Both
LPAL13_300019800 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_000048000
hypothetical protein, conserved
— Both
LPAL13_260011900
hypothetical protein, conserved
— Both
LPAL13_260028200
Zn-finger in Ran binding protein and others/S
— Both
LPAL13_070012900 ⚠
topoisomerase-related function protein-like p
— OG7
LPAL13_280035600 ⚠
receptor for activated C kinase 1
— OG7
LPAL13_280035700 ⚠
receptor for activated C kinase 1
— OG7
LPAL13_260009700 ⚠
DNA polymerase sigma-like protein
— OG7
LPAL13_350049100 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LPAL13_000008000 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LPAL13_200063900 ⚠
zinc-binding phosphatase, putative
— OG7
LPAL13_200027800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LPAL13_070006200 ⚠
Sec7 domain containing protein, putative
— OG7
LPAL13_350049200 ⚠
hypothetical protein
— OG7
LPAL13_310032300 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LPAL13_060009000
hypothetical protein, conserved
— Both
LPAL13_280034300
coatomer gamma subunit, putative
— Both
LPAL13_120008100 ⚠
Myotubularin-like phosphatase domain containi
— Both
LPAL13_300034700
eukaryotic translation initiation factor 3 su
— Both
LPAL13_040011200
hypothetical protein, conserved
— Both
LPAL13_310015300
hypothetical protein, conserved
— Both
LPAL13_040014200
hypothetical protein, conserved
— Both
LPAL13_330011600
hypothetical protein, conserved
— Both
LPAL13_350062300
glycosyl hydrolase, putative
— Both
LPAL13_140009400
mRNA capping enzyme, beta chain, putative
— Both
LPAL13_210017800
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LPAL13_140008000
hypothetical protein, conserved
— Both
LPAL13_180017700
NADH-ubiquinone oxidoreductase complex I subu
— Both
LPAL13_210011100
RNA helicase, putative
— Both
LPAL13_200024000
hypothetical protein, conserved
— Both
LPAL13_340027000
hypothetical protein, conserved
— Both
LPAL13_340039500
acyl transferase-like protein, putative
— Both
LPAL13_350081600
eukaryotic translation initiation factor 3 su
— Both
LPAL13_200026800 ⚠
Sec7 domain containing protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.