LPAL13_100007000

mitogen-activated protein kinase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_147455 OG7: OG7_0000396 114 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 114 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_270031600 ⚠
protein phosphatase-like protein
— OG6
LPAL13_180005300
mevalonate-diphosphate decarboxylase, putativ
— OG6
LPAL13_320045200
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— OG6
LPAL13_310016700
biotin/lipoate protein ligase-like protein
— OG6
LPAL13_000039300 ⚠
serine/threonine kinase-like protein, putativ
— OG6
LPAL13_330005800
hypothetical protein, conserved
— OG6
LPAL13_070014900 ⚠
serine/threonine kinase, putative
— OG6
LPAL13_290017800
carnitine/choline acetyltransferase, putative
— OG6
LPAL13_290008500
UBX domain-containing protein
— OG6
LPAL13_180007000
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
LPAL13_300030000
RNA-binding protein, putative
— OG6
LPAL13_280020600
haloacid dehalogenase-like hydrolase, putativ
— OG6
LPAL13_340013000 ⚠
aspartate aminotransferase, putative
— OG6
LPAL13_240008900 ⚠
aspartate aminotransferase, putative
— OG6
LPAL13_250023100
hypothetical protein, conserved
— OG6
LPAL13_320017000
exportin 1, putative
— OG6
LPAL13_320014700
Alpha/beta hydrolase family, putative
— OG6
LPAL13_000041700
hypothetical protein
— OG6
LPAL13_320027500 ⚠
Cytidylyltransferase, putative
— OG6
LPAL13_280017700
WD domain, G-beta repeat, putative
— OG6
LPAL13_180007800 ⚠
Dephospho-CoA kinase, putative
— OG6
LPAL13_270031700
GTP binding protein, putative
— OG6
LPAL13_350049000
hs1vu complex proteolytic subunit-like, threo
— OG6
LPAL13_300009200
phosphatase 2C, putative
— OG6
LPAL13_350010600 ⚠
protein phosphatase 2C-like protein
— OG6
LPAL13_280018000
electron-transfer-flavoprotein, alpha polypep
— OG6
LPAL13_320023400 ⚠
protein phosphatase 2C, putative
— OG6
LPAL13_230025700
alanine racemase, putative
— OG6
LPAL13_220008200
SEP domain containing protein, putative
— OG6
LPAL13_010006600
cyclophilin 12, putative
— OG6
LPAL13_120005100
PITH domain containing protein, putative
— OG6
LPAL13_180012800
UDP-glucose pyrophosphorylase
— OG6
LPAL13_000015200
hypothetical protein, conserved
— OG6
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— OG6
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— OG6
LPAL13_060016700
deoxyribose-phosphate aldolase, putative
— OG6
LPAL13_270014000
UBA/TS-N domain containing protein, putative
— OG6
LPAL13_200009800
Gamma-soluble NSF attachment protein (SNAP-ga
— OG6
LPAL13_080007800 ⚠
iron superoxide dismutase
— OG6
LPAL13_320033900 ⚠
superoxide dismutase, putative
— OG6
LPAL13_330037300
transcription elongation factor-like protein
— OG6
LPAL13_280005500
hypothetical protein, conserved
— OG6
LPAL13_330015000
nicotinate phosphoribosyltransferase, putativ
— OG6
LPAL13_270032300 ⚠
TPR-repeat protein, putative
— OG6
LPAL13_350011000
Elongation factor G1, mitochondrial, putative
— OG6
LPAL13_250024400
succinyl-CoA synthetase alpha subunit, putati
— OG6
LPAL13_350005400 ⚠
stress-inducible protein STI1 homolog
— OG6
LPAL13_200055200
hypothetical protein, conserved
— OG6
LPAL13_160005400
2OG-Fe(II) oxygenase superfamily, putative
— OG6
LPAL13_200041400
phosphomannomutase-like protein
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.