LPAL13_270032300

TPR-repeat protein, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_103410 OG7: OG7_0001150 152 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 152 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_000036300 ⚠
ABC transport system ATP-binding protein, put
— OG6
LPAL13_000041700 ⚠
hypothetical protein
— OG6
LPAL13_320027500 ⚠
Cytidylyltransferase, putative
— OG6
LPAL13_280017700 ⚠
WD domain, G-beta repeat, putative
— OG6
LPAL13_180007800 ⚠
Dephospho-CoA kinase, putative
— OG6
LPAL13_350010600 ⚠
protein phosphatase 2C-like protein
— OG6
LPAL13_280018000 ⚠
electron-transfer-flavoprotein, alpha polypep
— OG6
LPAL13_230025700 ⚠
alanine racemase, putative
— OG6
LPAL13_320023400 ⚠
protein phosphatase 2C, putative
— OG6
LPAL13_220008200 ⚠
SEP domain containing protein, putative
— OG6
LPAL13_270031600 ⚠
protein phosphatase-like protein
— OG6
LPAL13_200041400 ⚠
phosphomannomutase-like protein
— OG6
LPAL13_200065400 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG6
LPAL13_270010200 ⚠
nucleoporin, putative
— OG6
LPAL13_350028700 ⚠
NOL1/NOP2/sun family, putative
— OG6
LPAL13_340052000 ⚠
Cysteine-rich motif following a subset of SET
— OG6
LPAL13_000015200 ⚠
hypothetical protein, conserved
— OG6
LPAL13_280031500 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG6
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— OG6
LPAL13_000050400 ⚠
methionyl-tRNA synthetase
— OG6
LPAL13_180011700 ⚠
cyclosporin 16, putative
— OG6
LPAL13_200022000 ⚠
pyroglutamyl-peptidase I (C15 family)
— OG6
LPAL13_230006000 ⚠
GDP-mannose pyrophosphorylase
— OG6
LPAL13_200051400 ⚠
deoxyhypusine synthase, putative
— OG6
LPAL13_140009600 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG6
LPAL13_290005600 ⚠
tryptophanyl-tRNA synthetase, putative
— OG6
LPAL13_200060000 ⚠
Pre-mRNA-splicing factor 38, putative
— OG6
LPAL13_270008900 ⚠
protein kinase, putative
— OG6
LPAL13_290023500 ⚠
UDP-glucose:Glycoprotein Glucosyltransferase,
— OG6
LPAL13_200041100 ⚠
hypothetical protein, conserved
— OG6
LPAL13_140017300 ⚠
YjeF family N-terminal domain/YjeF family C-t
— OG6
LPAL13_350066100 ⚠
isoleucyl-tRNA synthetase, putative
— OG6
LPAL13_290020600 ⚠
XPC-binding domain/UBA/TS-N domain containing
— OG6
LPAL13_100007000 ⚠
mitogen-activated protein kinase, putative
— OG6
LPAL13_340008400 ⚠
hypothetical protein, conserved
— OG6
LPAL13_290008500 ⚠
UBX domain-containing protein
— OG6
LPAL13_050008100 ⚠
trypanothione reductase
— OG6
LPAL13_140019600 ⚠
tyrosyl-tRNA synthetase, putative
— OG6
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— OG6
LPAL13_350011000 ⚠
Elongation factor G1, mitochondrial, putative
— OG6
LPAL13_200055200 ⚠
hypothetical protein, conserved
— OG6
LPAL13_210005300 ⚠
ALIX V-shaped domain binding to HIV, putative
— OG6
LPAL13_280028200 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG6
LPAL13_220017900 ⚠
alanyl-tRNA synthetase, putative
— OG6
LPAL13_320005800 ⚠
N-myristoyl transferase, putative
— OG6
LPAL13_310006400 ⚠
ubiquitin hydrolase, putative
— OG6
LPAL13_050012700 ⚠
hypothetical protein, conserved
— OG6
LPAL13_010006600 ⚠
cyclophilin 12, putative
— OG6
LPAL13_180012800 ⚠
UDP-glucose pyrophosphorylase
— OG6
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.