LPAL13_000050400

methionyl-tRNA synthetase

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101119 OG7: OG7_0003306 127 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

Applies on "Apply filters".

Reset

⬇ CSV

Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 127 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_300011800 histidyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003126 ↔ TCSYLVIO_007991 OG6 Tb927.10.1500 ↔ Tb927.6.2060 OG7 TCSYLVIO_003126 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.6.2060	Both
LPAL13_160015700 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 Tb927.10.1500 ↔ Tb927.7.2400 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
LPAL13_140019600 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.7.3620 OG6 TCSYLVIO_007991 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
LPAL13_130014400 leucyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007991	Both
LPAL13_300035800 valyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.6.4480 OG6 TCSYLVIO_003345 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.6.4480 OG7 TCSYLVIO_003345 ↔ TCSYLVIO_007991	Both
LPAL13_220009500 ⚠ Putative tRNA binding domain containing prote	—	OG6 Tb927.10.1500 ↔ Tb927.7.2400 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
LPAL13_000049800 ⚠ hypothetical protein	—	OG7 TCSYLVIO_007387 ↔ TCSYLVIO_007991	OG7
LPAL13_340008700 Thioredoxin, putative	—	OG6 TCSYLVIO_005083 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005083 ↔ TCSYLVIO_007991	Both
LPAL13_220008000 hypothetical protein, conserved	—	OG6 TCSYLVIO_001161 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_007991	Both
LPAL13_300039000 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007991	Both
LPAL13_200060000 Pre-mRNA-splicing factor 38, putative	—	OG6 TCSYLVIO_007337 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007337 ↔ TCSYLVIO_007991	Both
LPAL13_300037600 UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007991	Both
LPAL13_180005200 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007991	Both
LPAL13_330034700 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_007991	Both
LPAL13_250024300 hypothetical protein, conserved	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_007991	Both
LPAL13_180006000 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_006140 ↔ TCSYLVIO_007991 OG6 TCSYLVIO_006141 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007991	Both
LPAL13_220014600 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007991	Both
LPAL13_340008900 hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_007991	Both
LPAL13_350028700 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	Both
LPAL13_290027900 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	Both
LPAL13_290023500 UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007991	Both
LPAL13_270032300 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007991	OG6
LPAL13_350005400 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007991	OG6
LPAL13_250006900 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007991	Both
LPAL13_220017900 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007991	Both
LPAL13_050012700 hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007991	Both
LPAL13_280009900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007991 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007991	Both
LPAL13_350066100 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007991	Both
LPAL13_300010100 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007991	Both
LPAL13_210014900 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007991	Both
LPAL13_320048400 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007991	Both
LPAL13_300013000 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_007991	Both
LPAL13_230006000 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
LPAL13_190005800 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007991	Both
LPAL13_030013300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007991	Both
LPAL13_000036300 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007991	Both
LPAL13_330016800 hypothetical protein, conserved	—	OG6 TCSYLVIO_004910 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004910 ↔ TCSYLVIO_007991	Both
LPAL13_230008600 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_010724	OG7
LPAL13_170017300 ⚠ NOL1/NOP2/sun family, putative	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	OG7
LPAL13_180014400 ⚠ Multisite-specific tRNA:(cytosine-C(5))-methy	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	OG7
LPAL13_350010000 ⚠ dihydrouridine synthase domain protein-like p	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_009102	OG7
LPAL13_030010800 hypothetical protein, conserved	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_007991 ↔ TCSYLVIO_010148	OG7
LPAL13_200017000 ⚠ Dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_009102	OG7
LPAL13_310024900 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_009102	OG7
LPAL13_300012600 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_010327	OG7
LPAL13_290011700 ⚠ heat shock protein 90, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_007991	OG7
LPAL13_210005200 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007991	OG7
LPAL13_210005300 ⚠ ALIX V-shaped domain binding to HIV, putative	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007991	OG7
LPAL13_240021700 ⚠ translation initiation factor IF-2, putative	—	OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007991	OG7
LPAL13_340034200 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007991	OG7

Page 1 of 3