LPAL13_000050400

methionyl-tRNA synthetase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101119 OG7: OG7_0003306 127 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 127 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_300011800
histidyl-tRNA synthetase, putative
— Both
LPAL13_160015700 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— +2 more Both
LPAL13_140019600 ⚠
tyrosyl-tRNA synthetase, putative
— +2 more Both
LPAL13_130014400
leucyl-tRNA synthetase, putative
— Both
LPAL13_300035800
valyl-tRNA synthetase, putative
— Both
LPAL13_220009500 ⚠
Putative tRNA binding domain containing prote
— +2 more Both
LPAL13_000049800 ⚠
hypothetical protein
— OG7
LPAL13_340008700
Thioredoxin, putative
— Both
LPAL13_220008000
hypothetical protein, conserved
— Both
LPAL13_300039000 ⚠
DNA ligase I, putative
— Both
LPAL13_200060000
Pre-mRNA-splicing factor 38, putative
— Both
LPAL13_300037600
UV excision repair RAD23-like protein
— Both
LPAL13_180005200 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LPAL13_330034700 ⚠
aminopeptidase, putative
— Both
LPAL13_250024300
hypothetical protein, conserved
— Both
LPAL13_180006000 ⚠
alpha glucosidase II subunit, putative
— Both
LPAL13_220014600 ⚠
translation initiation factor IF-2, putative
— Both
LPAL13_340008900
hypothetical protein, conserved
— Both
LPAL13_350028700 ⚠
NOL1/NOP2/sun family, putative
— Both
LPAL13_290027900 ⚠
NOL1/NOP2/sun family, putative
— Both
LPAL13_290023500
UDP-glucose:Glycoprotein Glucosyltransferase,
— Both
LPAL13_270032300 ⚠
TPR-repeat protein, putative
— OG6
LPAL13_350005400 ⚠
stress-inducible protein STI1 homolog
— OG6
LPAL13_250006900 ⚠
cleavage and polyadenylation specificity fact
— Both
LPAL13_220017900
alanyl-tRNA synthetase, putative
— Both
LPAL13_050012700
hypothetical protein, conserved
— Both
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— Both
LPAL13_350066100
isoleucyl-tRNA synthetase, putative
— Both
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— Both
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— Both
LPAL13_320048400
Gar1/Naf1 RNA binding region containing prote
— Both
LPAL13_300013000 ⚠
co-chaperone GrpE, putative
— Both
LPAL13_230006000
GDP-mannose pyrophosphorylase
— Both
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— Both
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_000036300 ⚠
ABC transport system ATP-binding protein, put
— Both
LPAL13_330016800
hypothetical protein, conserved
— Both
LPAL13_230008600 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LPAL13_170017300 ⚠
NOL1/NOP2/sun family, putative
— OG7
LPAL13_180014400 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_030010800
hypothetical protein, conserved
— OG7
LPAL13_200017000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_310024900 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LPAL13_300012600 ⚠
nuclear movement protein, putative
— OG7
LPAL13_290011700 ⚠
heat shock protein 90, putative
— OG7
LPAL13_210005200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_210005300 ⚠
ALIX V-shaped domain binding to HIV, putative
— OG7
LPAL13_240021700 ⚠
translation initiation factor IF-2, putative
— OG7
LPAL13_340034200 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.