LPAL13_300039000

DNA ligase I, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100906 OG7: OG7_0002598 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_310024900 ⚠
dihydrouridine synthase (Dus), putative
— Both
LPAL13_030011800 ⚠
Ubiquitin-like domain containing protein, put
— Both
LPAL13_200017000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LPAL13_080008000 ⚠
Isochorismatase family, putative
— OG7
LPAL13_250014900 ⚠
protein kinase, putative
— Both
LPAL13_350005400 ⚠
stress-inducible protein STI1 homolog
— OG6
LPAL13_330007300 ⚠
hypothetical protein, conserved
— Both
LPAL13_350006200 ⚠
PUB domain containing protein, putative
— Both
LPAL13_140018600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LPAL13_250027500 ⚠
hypothetical protein, conserved
— Both
LPAL13_340008900 ⚠
hypothetical protein, conserved
— Both
LPAL13_210024500 ⚠
SET domain containing protein, putative
— Both
LPAL13_300037600 ⚠
UV excision repair RAD23-like protein
— Both
LPAL13_180005200 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LPAL13_200056400 ⚠
tubulin-tyrosine ligase, putative
— Both
LPAL13_220014600 ⚠
translation initiation factor IF-2, putative
— Both
LPAL13_270015500 ⚠
WD40 repeats, putative
— Both
LPAL13_300035500 ⚠
S-adenosylmethionine decarboxylase
— Both
LPAL13_280023400 ⚠
phosphonopyruvate decarboxylase-like protein
— Both
LPAL13_000014700
casein kinase II, alpha chain, putative
— OG6
LPAL13_220017900 ⚠
alanyl-tRNA synthetase, putative
— Both
LPAL13_050012700 ⚠
hypothetical protein, conserved
— Both
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— Both
LPAL13_210015700 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LPAL13_280025800 ⚠
replication factor A, 51kDa subunit, putative
— Both
LPAL13_220013700 ⚠
Beta-lactamase superfamily domain containing
— Both
LPAL13_220013600 ⚠
Beta-lactamase superfamily domain containing
— Both
LPAL13_320048400 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LPAL13_030011600 ⚠
TatD related DNase, putative
— Both
LPAL13_230025600 ⚠
hypothetical protein, conserved
— Both
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— Both
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_280008700 ⚠
rrp44p homologue, putative
— OG7
LPAL13_040008700 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LPAL13_100011500 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LPAL13_260025100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_080007900 ⚠
Isochorismatase family, putative
— OG7
LPAL13_300026700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_180008600 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_210005200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300012600 ⚠
nuclear movement protein, putative
— OG7
LPAL13_320006000 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_200037300 ⚠
cleavage and polyadenylation specificity fact
— OG7
LPAL13_030006400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LPAL13_340040300 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LPAL13_330008100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.