LPAL13_190005800

acidocalcisomal pyrophosphatase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100346 OG7: OG7_0003350 290 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 290 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_080007000 ⚠
ubiquitin-activating enzyme-like protein
— Both
LPAL13_230006000 ⚠
GDP-mannose pyrophosphorylase
— Both
LPAL13_040010400 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_200060400 ⚠
hypothetical protein, conserved
— OG6
LPAL13_200060300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_000020300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_200060500 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LPAL13_340005000 ⚠
pyruvate kinase
— Both
LPAL13_250024300 ⚠
hypothetical protein, conserved
— Both
LPAL13_320046100 ⚠
Methyltransferase TYW3, putative
— OG7
LPAL13_270032500 ⚠
aldo-keto reductase-like protein
— OG7
LPAL13_310035400 ⚠
aldehyde reductase, putative
— OG7
LPAL13_000034100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_130006500 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_330034700 ⚠
aminopeptidase, putative
— OG7
LPAL13_310007900 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LPAL13_000031000 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_130019500 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_240027300 ⚠
tubulin folding cofactor D, putative
— Both
LPAL13_100018300 ⚠
hypothetical protein, conserved
— Both
LPAL13_150005300 ⚠
Possible lysine decarboxylase, putative
— Both
LPAL13_350079300 ⚠
beta-adaptin, putative
— Both
LPAL13_340008900 ⚠
hypothetical protein, conserved
— Both
LPAL13_250027500 ⚠
hypothetical protein, conserved
— Both
LPAL13_250023000 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LPAL13_220014600 ⚠
translation initiation factor IF-2, putative
— Both
LPAL13_300011100 ⚠
hypothetical protein, conserved
— Both
LPAL13_340018800 ⚠
threonyl-tRNA synthetase, putative
— Both
LPAL13_350078100 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LPAL13_080009200 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_140018600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LPAL13_340047800 ⚠
Protein of unknown function (DUF2009), putati
— Both
LPAL13_350006200 ⚠
PUB domain containing protein, putative
— Both
LPAL13_350054400 ⚠
Protein of unknown function (DUF2870), putati
— Both
LPAL13_250023100 ⚠
hypothetical protein, conserved
— Both
LPAL13_270031600 ⚠
protein phosphatase-like protein
— OG6
LPAL13_100008100 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LPAL13_260014500 ⚠
Glucosidase II beta subunit-like protein, put
— Both
LPAL13_200025800 ⚠
Uncharacterized conserved protein H4 (DUF2046
— Both
LPAL13_320045200 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— Both
LPAL13_060015400 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— Both
LPAL13_210011400 ⚠
phosphoglucomutase, putative
— Both
LPAL13_350014900 ⚠
eukaryotic translation initiation factor 6 (e
— Both
LPAL13_000018300 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LPAL13_030009700 ⚠
quinone oxidoreductase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.