LPAL13_320045200

3-hydroxyisobutyryl-coenzyme A hydrolase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102025 OG7: OG7_0000750 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_160011300 ⚠
transaldolase, putative
— Both
LPAL13_000053700 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LPAL13_100008100 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LPAL13_270031600 ⚠
protein phosphatase-like protein
— OG6
LPAL13_340047800 ⚠
Protein of unknown function (DUF2009), putati
— Both
LPAL13_250023100 ⚠
hypothetical protein, conserved
— Both
LPAL13_250023000 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LPAL13_010011900 ⚠
eukaryotic initiation factor 4a, putative
— Both
LPAL13_290017800 ⚠
carnitine/choline acetyltransferase, putative
— Both
LPAL13_300030000
RNA-binding protein, putative
— OG6
LPAL13_280020600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LPAL13_340013000 ⚠
aspartate aminotransferase, putative
— Both
LPAL13_240008900 ⚠
aspartate aminotransferase, putative
— Both
LPAL13_320014700 ⚠
Alpha/beta hydrolase family, putative
— Both
LPAL13_000041700 ⚠
hypothetical protein
— Both
LPAL13_320027500 ⚠
Cytidylyltransferase, putative
— Both
LPAL13_280017700 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_180007800 ⚠
Dephospho-CoA kinase, putative
— Both
LPAL13_280018000 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LPAL13_230025700 ⚠
alanine racemase, putative
— Both
LPAL13_220008200 ⚠
SEP domain containing protein, putative
— Both
LPAL13_200041400 ⚠
phosphomannomutase-like protein
— Both
LPAL13_200037800 ⚠
amidinotransferase, putative
— Both
LPAL13_280028200 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LPAL13_310006400 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_010006600
cyclophilin 12, putative
— OG6
LPAL13_330015000 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
LPAL13_330037300 ⚠
transcription elongation factor-like protein
— Both
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— Both
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_130019500 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_000031000 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_310007900 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LPAL13_350045600 ⚠
nudix hydrolase-like protein
— OG7
LPAL13_330010300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_130006500 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_280020800 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LPAL13_340008600 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LPAL13_210021700 ⚠
RNA helicase, putative
— OG7
LPAL13_280022700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LPAL13_070005500 ⚠
alpha-adaptin-like protein
— OG7
LPAL13_200043500 ⚠
adaptor gamma-1 chain, putative
— OG7
LPAL13_190021500 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LPAL13_220008100 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LPAL13_250016600 ⚠
dehydrogenase-like protein
— OG7
LPAL13_280020700 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_240007000 ⚠
transcription elongation factor, putative
— OG7
LPAL13_010006500 ⚠
UBA/TS-N domain/CUE domain/Domain of unknown
— OG7
LPAL13_170017500 ⚠
5'-3' exonuclease, putative
— OG7
LPAL13_280020400 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.