LPAL13_170017500

5'-3' exonuclease, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_156818 OG7: OG7_0003221 192 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 192 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_250021300 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG7
LPAL13_220008100 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LPAL13_350078100 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LPAL13_280020700 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_260023400 ⚠
deoxyhypusine hydroxylase, putative
— OG7
LPAL13_300015000 ⚠
conserved hypothetical protein, putative
— OG7
LPAL13_280027500 ⚠
protein kinase, putative
— OG7
LPAL13_250023000 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
LPAL13_300006900 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
LPAL13_190020800 ⚠
eukaryotic translation initiation factor-like
— OG7
LPAL13_320015300 ⚠
ubiquitin-conjugating enzyme protein, putativ
— OG7
LPAL13_160020100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_220006200 ⚠
glutamine amidotransferase, putative
— OG7
LPAL13_200059700 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_320021000 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_160018300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300010400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_290016400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_240026700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_050008500 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LPAL13_330040100 ⚠
46 kD virulence factor
— OG7
LPAL13_320048300 ⚠
cAMP response protein, putative
— OG7
LPAL13_140012900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200027800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LPAL13_340040200 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LPAL13_200051500 ⚠
Midasin, putative
— OG7
LPAL13_260023800 ⚠
microtubule-associated protein, putative
— OG7
LPAL13_130006800 ⚠
protein kinase A regulatory subunit, putative
— OG7
LPAL13_120005000 ⚠
translation initiation factor EIF-2b alpha su
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_210020100 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LPAL13_350073800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_000013100 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_160020600 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_100015300 ⚠
Translation initiation factor eIF-2B subunit
— OG7
LPAL13_330040000 ⚠
hypothetical protein
— OG7
LPAL13_330039900 ⚠
46 kD virulence factor
— OG7
LPAL13_330011600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300005600 ⚠
MATH domain containing protein, putative
— OG7
LPAL13_140014200 ⚠
tc40 antigen-like
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_320008200 ⚠
WD40 repeats, putative
— OG7
LPAL13_330022300 ⚠
Tetratricopeptide repeats, putative
— OG7
LPAL13_190009000 ⚠
fibrillarin, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.