LPAL13_140012900

hypothetical protein, conserved
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_147780 OG7: OG7_0083509 83 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 83 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_040015200
Axonemal dynein light chain, putative
— Both
LPAL13_200059700 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_200026800 ⚠
Sec7 domain containing protein, putative
— OG7
LPAL13_200027800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LPAL13_270019300 ⚠
translation initiation factor eIF2B subunit-l
— OG7
LPAL13_100015300 ⚠
Translation initiation factor eIF-2B subunit
— OG7
LPAL13_090017700
AAA family ATPase, putative
— Both
LPAL13_120005000 ⚠
translation initiation factor EIF-2b alpha su
— Both
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LPAL13_090013500
kinetoplast-associated protein-like protein
— OG6
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— Both
LPAL13_040011400
Tetratricopeptide repeat/TPR repeat, putative
— Both
LPAL13_100016400
hypothetical protein, conserved
— Both
LPAL13_110013600 ⚠
40S ribosomal protein S5
— Both
LPAL13_110013500 ⚠
Ribosomal protein S7p/S5e, putative
— Both
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— Both
LPAL13_060007900 ⚠
5'-3' exonuclease, putative
— Both
LPAL13_350024400 ⚠
exoribonuclease 2, putative
— Both
LPAL13_160020600 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_240014200 ⚠
dynein arm light chain, putative
— OG7
LPAL13_130018000 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_000022100 ⚠
tubulin-specific chaperone, putative
— OG7
LPAL13_210016400 ⚠
dynein arm light chain, putative
— OG7
LPAL13_210022300 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LPAL13_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LPAL13_330017500 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LPAL13_200031200 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LPAL13_330039900 ⚠
46 kD virulence factor
— OG7
LPAL13_330040000 ⚠
hypothetical protein
— OG7
LPAL13_330022300
Tetratricopeptide repeats, putative
— Both
LPAL13_130006800 ⚠
protein kinase A regulatory subunit, putative
— OG7
LPAL13_340040200 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LPAL13_330040100 ⚠
46 kD virulence factor
— OG7
LPAL13_320048300 ⚠
cAMP response protein, putative
— OG7
LPAL13_170017500 ⚠
5'-3' exonuclease, putative
— OG7
LPAL13_030007500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_030007400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_320021000 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LPAL13_200051500
Midasin, putative
— Both
LPAL13_140014200
tc40 antigen-like
— Both
LPAL13_220010400
proteasome regulatory ATPase subunit 1, putat
— OG6
LPAL13_300005600
MATH domain containing protein, putative
— Both
LPAL13_320012200
OSM3-like kinesin, putative
— OG6
LPAL13_000013100
WD domain, G-beta repeat, putative
— Both
LPAL13_350073800 ⚠
ubiquitin-protein ligase, putative
— Both
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.