LPAL13_340040200

structural maintenance of chromosome (SMC) family protein, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101499 OG7: OG7_0001761 211 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 211 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_180011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310006600 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_230011900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_210010300 ⚠
Tetratricopeptide repeat, putative
— OG7
LPAL13_320020000 ⚠
RNA guanylyltransferase, putative
— OG7
LPAL13_350015900 ⚠
intraflagellar transport protein IFT122, puta
— OG7
LPAL13_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_320037000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_300012200 ⚠
Phosphoinositide-specific phospholipase C, ef
— OG7
LPAL13_160018400 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LPAL13_000015500 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LPAL13_080012300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LPAL13_000050500 ⚠
Domain of unknown function (DUF3819)/CCR4-Not
— OG7
LPAL13_340029400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_330017500 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LPAL13_340028700 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_330037000 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LPAL13_230017400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_040016300 ⚠
adenylate kinase, putative
— OG7
LPAL13_150016400 ⚠
protein kinase, putative
— OG7
LPAL13_200031200 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LPAL13_000008900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350038900 ⚠
cullin-like protein
— OG7
LPAL13_260015900 ⚠
Axonemal dynein light chain, putative
— OG7
LPAL13_240023600 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_290006400 ⚠
DNA-directed RNA polymerase I-like protein
— OG7
LPAL13_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LPAL13_330029100 ⚠
mitogen-activated protein kinase, putative
— OG7
LPAL13_280021800 ⚠
Cell division control protein 48, putative
— OG7
LPAL13_110006100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_150011400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340048700 ⚠
predicted zinc finger protein
— OG7
LPAL13_350073800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_350031300 ⚠
Cullin protein neddylation domain containing
— OG7
LPAL13_110013800 ⚠
adaptin-related protein-like protein
— OG7
LPAL13_000013100 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_160020600 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_340027000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300018300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_240016400 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LPAL13_300026000 ⚠
endosomal trafficking protein RME-8, putative
— OG7
LPAL13_180011200 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LPAL13_220018900 ⚠
CCR4 associated factor, putative
— OG7
LPAL13_330027400 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_260015500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350029600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_250021300 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG7
LPAL13_300005600 ⚠
MATH domain containing protein, putative
— OG7
LPAL13_330040000 ⚠
hypothetical protein
— OG7
LPAL13_330039900 ⚠
46 kD virulence factor
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.