LPAL13_220018900

CCR4 associated factor, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101138 OG7: OG7_0005422 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_230005000
hypothetical protein, conserved
— Both
LPAL13_000050500
Domain of unknown function (DUF3819)/CCR4-Not
— Both
LPAL13_250021300
Not1 N-terminal domain, CCR4-Not complex comp
— Both
LPAL13_120008500
CCR4-NOT transcription complex subunit 2, put
— Both
LPAL13_200047500
cell differentiation protein-like protein
— Both
LPAL13_320021000 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LPAL13_270033200
WD-repeat protein
— Both
LPAL13_040015200
Axonemal dynein light chain, putative
— Both
LPAL13_150011900
hypothetical protein, conserved
— Both
LPAL13_220018500
hypothetical protein, conserved
— Both
LPAL13_140010800
WD domain, G-beta repeat, putative
— Both
LPAL13_120010700 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LPAL13_060017800
hypothetical protein, conserved
— Both
LPAL13_160008100 ⚠
tubulin tyrosine ligase, putative
— Both
LPAL13_090017700
AAA family ATPase, putative
— Both
LPAL13_300025800
RNA-binding protein, putative
— OG6
LPAL13_050014900 ⚠
MORN repeat, putative
— OG7
LPAL13_200027800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LPAL13_200026800 ⚠
Sec7 domain containing protein, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_050008700 ⚠
Tetratricopeptide repeat/TPR repeat, putative
— OG7
LPAL13_300026700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_180008600 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LPAL13_340055500 ⚠
tubulin tyrosine ligase, putative
— OG7
LPAL13_270033300 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_290007700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LPAL13_200056400 ⚠
tubulin-tyrosine ligase, putative
— OG7
LPAL13_110006400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LPAL13_320037200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_300038300
hypothetical protein, conserved
— OG7
LPAL13_200048300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_240029900 ⚠
cullin-like protein-like protein
— OG7
LPAL13_350044000 ⚠
Ubiquitin family, putative
— OG7
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_000014300 ⚠
ubiquitin-fusion protein
— OG7
LPAL13_350031300 ⚠
Cullin protein neddylation domain containing
— OG7
LPAL13_310032300 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LPAL13_090007400 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LPAL13_230026800 ⚠
neutral sphingomyelinase activation associate
— OG7
LPAL13_340055400 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LPAL13_240014900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LPAL13_170015100 ⚠
formin, putative
— OG7
LPAL13_350023700 ⚠
neurobeachin/beige protein, putative
— OG7
LPAL13_130018000 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_350079300 ⚠
beta-adaptin, putative
— OG7
LPAL13_340040200 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.