LPAL13_120010700

TPR repeat/Tetratricopeptide repeat, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102790 OG7: OG7_0003813 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_040009400 ⚠
Anaphase-promoting complex, subunit 10 (APC10
— +2 more Both
LPAL13_050008700 ⚠
Tetratricopeptide repeat/TPR repeat, putative
— Both
LPAL13_040009500 ⚠
anaphase promoting complex, subunit 10-like p
— +2 more Both
LPAL13_060017800 ⚠
hypothetical protein, conserved
— +1 more Both
LPAL13_300023800 ⚠
cyclosome subunit-like protein
— +2 more Both
LPAL13_240015100 ⚠
hypothetical protein, conserved
— +2 more Both
LPAL13_300012800 ⚠
CDC16, putative
— +2 more Both
LPAL13_210023800 ⚠
hypothetical protein, conserved
— Both
LPAL13_160010100 ⚠
RING-H2 zinc finger containing protein, putat
— OG7
LPAL13_170009300 ⚠
hypothetical protein, conserved
— Both
LPAL13_290014300
kinesin, putative
— OG6
LPAL13_000022500 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_170007400 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LPAL13_230005000 ⚠
hypothetical protein, conserved
— Both
LPAL13_270033200 ⚠
WD-repeat protein
— Both
LPAL13_090017700 ⚠
AAA family ATPase, putative
— Both
LPAL13_050014900 ⚠
MORN repeat, putative
— OG7
LPAL13_200027800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LPAL13_200026800 ⚠
Sec7 domain containing protein, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_320048300 ⚠
cAMP response protein, putative
— OG7
LPAL13_050008500 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LPAL13_310033600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_110006600 ⚠
chromatin binding protein, putative
— OG7
LPAL13_340040200 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LPAL13_130006800 ⚠
protein kinase A regulatory subunit, putative
— OG7
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_340031100 ⚠
ankyrin repeat protein, putative
— OG7
LPAL13_200037300 ⚠
cleavage and polyadenylation specificity fact
— OG7
LPAL13_240022900 ⚠
ring-box protein, putative
— OG7
LPAL13_160010200 ⚠
ring-box protein 1, putative
— OG7
LPAL13_320039800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_260012100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_350033700 ⚠
cyclin-e binding protein 1-like protein
— OG7
LPAL13_200061200 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LPAL13_130018000 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_090014400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200020000 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LPAL13_300037200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_350049800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_030007500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200031200 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LPAL13_200022200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_330006500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_290015500 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.