LPAL13_220018500

hypothetical protein, conserved
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_158221 OG7: OG7_0052244 109 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 109 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_350044100 ⚠
polyubiquitin, putative
— OG7
LPAL13_200048300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_240029900 ⚠
cullin-like protein-like protein
— OG7
LPAL13_200059700 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LPAL13_350044000 ⚠
Ubiquitin family, putative
— OG7
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_000014300 ⚠
ubiquitin-fusion protein
— OG7
LPAL13_280006400 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
LPAL13_350031300 ⚠
Cullin protein neddylation domain containing
— OG7
LPAL13_110013800 ⚠
adaptin-related protein-like protein
— OG7
LPAL13_320021000 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LPAL13_320037500 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LPAL13_000008000 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LPAL13_050007900 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LPAL13_190012200 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LPAL13_240023600 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_000026200 ⚠
Ubiquitin family, putative
— OG7
LPAL13_350038900 ⚠
cullin-like protein
— OG7
LPAL13_280031700 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LPAL13_330037000 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_310006600 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_140018100 ⚠
Ribosomal protein S27a, putative
— OG7
LPAL13_160017100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_170015200 ⚠
formin, putative
— OG7
LPAL13_180008600 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LPAL13_300038900 ⚠
protein mkt1, putative
— OG7
LPAL13_260009700 ⚠
DNA polymerase sigma-like protein
— OG7
LPAL13_350049100 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LPAL13_040010900 ⚠
Nucleotidyltransferase domain/Cid1 family pol
— OG7
LPAL13_350049200 ⚠
hypothetical protein
— OG7
LPAL13_200007500 ⚠
RNA polymerase ii largest subunit
— OG7
LPAL13_310031800 ⚠
RNA polymerase ii largest subunit
— OG7
LPAL13_320037200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_110006400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LPAL13_200056400 ⚠
tubulin-tyrosine ligase, putative
— OG7
LPAL13_290007700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LPAL13_270033300 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_340055500 ⚠
tubulin tyrosine ligase, putative
— OG7
LPAL13_350023700 ⚠
neurobeachin/beige protein, putative
— OG7
LPAL13_330036100 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LPAL13_090007400 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LPAL13_230026800 ⚠
neutral sphingomyelinase activation associate
— OG7
LPAL13_340055400 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LPAL13_240014900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LPAL13_170015100 ⚠
formin, putative
— OG7
LPAL13_060010600 ⚠
SpoU rRNA Methylase family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.