LPAL13_320037200

tubulin-tyrosine ligase-like protein
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_173725 OG7: OG7_0001164 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_250018800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000008900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280031700 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LPAL13_330037000 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LPAL13_200022600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200039000 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LPAL13_160018400 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_320014100 ⚠
RNA recognition motif containing protein, put
— OG7
LPAL13_220018500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350011700 ⚠
DNAJ protein-like protein
— OG7
LPAL13_310024900 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LPAL13_310006600 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_140018100 ⚠
Ribosomal protein S27a, putative
— OG7
LPAL13_160017100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_000037100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_170015200 ⚠
formin, putative
— OG7
LPAL13_200044700 ⚠
GRIP domain containing protein, putative
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_350036000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350044100 ⚠
polyubiquitin, putative
— OG7
LPAL13_330036100 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LPAL13_310025500 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LPAL13_090007400 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LPAL13_260025200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200042400 ⚠
DnaJ domain containing protein, putative
— OG7
LPAL13_230026800 ⚠
neutral sphingomyelinase activation associate
— OG7
LPAL13_270015100 ⚠
parallel beta-helix repeat, putative
— OG7
LPAL13_300039000 ⚠
DNA ligase I, putative
— OG7
LPAL13_240016900 ⚠
formin, putative
— OG7
LPAL13_340055400 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LPAL13_240014900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LPAL13_220013700 ⚠
Beta-lactamase superfamily domain containing
— OG7
LPAL13_220013600 ⚠
Beta-lactamase superfamily domain containing
— OG7
LPAL13_070006000 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LPAL13_060009500 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
LPAL13_350018500 ⚠
fructose-1,6-bisphosphate aldolase
— OG7
LPAL13_060009400 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
LPAL13_130015800 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
LPAL13_150016100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_030010000 ⚠
kinase-like protein
— OG7
LPAL13_110006100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_040010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_140010800 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_070011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_110007100 ⚠
pumillio protein 10, putative
— OG7
LPAL13_280006700 ⚠
RNA binding protein, putative
— OG7
LPAL13_070016200 ⚠
peptidyl-prolyl cis-trans isomerase/rotamase,
— OG7
LPAL13_040007100 ⚠
exosome complex exonuclease RRP40, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.