LPAL13_000050500

Domain of unknown function (DUF3819)/CCR4-Not complex component, Not1, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101511 OG7: OG7_0005420 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_120008500
CCR4-NOT transcription complex subunit 2, put
— +2 more Both
LPAL13_250021300
Not1 N-terminal domain, CCR4-Not complex comp
— Both
LPAL13_220018900
CCR4 associated factor, putative
— Both
LPAL13_200047500
cell differentiation protein-like protein
— Both
LPAL13_270032400 ⚠
heat shock protein DNAJ, putative
— Both
LPAL13_210009700 ⚠
DnaJ protein, putative
— Both
LPAL13_270020900
hypothetical protein, conserved
— Both
LPAL13_200014900
EF hand/EF-hand domain pair, putative
— Both
LPAL13_230005000
hypothetical protein, conserved
— Both
LPAL13_350071000
CCR4-NOT transcription complex subunit 10, pu
— Both
LPAL13_150016400 ⚠
protein kinase, putative
— Both
LPAL13_050008500 ⚠
structural maintenance of chromosome (SMC), p
— Both
LPAL13_290030100
hypothetical protein, conserved
— Both
LPAL13_120006100 ⚠
FYVE zinc finger containing protein, putative
— Both
LPAL13_050013900
paraflagellar rod protein, putative
— Both
LPAL13_070006200 ⚠
Sec7 domain containing protein, putative
— Both
LPAL13_110011800
hypothetical protein, conserved
— Both
LPAL13_350039000 ⚠
fibrillarin
— Both
LPAL13_190009000 ⚠
fibrillarin, putative
— Both
LPAL13_140012900
hypothetical protein, conserved
— Both
LPAL13_000022500
WD domain, G-beta repeat, putative
— Both
LPAL13_190016000 ⚠
CAP-Gly domain containing protein, putative
— Both
LPAL13_350024400 ⚠
exoribonuclease 2, putative
— Both
LPAL13_060007900 ⚠
5'-3' exonuclease, putative
— Both
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— Both
LPAL13_210010300
Tetratricopeptide repeat, putative
— Both
LPAL13_100016400
hypothetical protein, conserved
— Both
LPAL13_040011400
Tetratricopeptide repeat/TPR repeat, putative
— Both
LPAL13_110007800
mRNA cap guanine-N7 methyltransferase, putati
— Both
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— Both
LPAL13_300010400
hypothetical protein, conserved
— Both
LPAL13_290016400
hypothetical protein, conserved
— Both
LPAL13_240026700
hypothetical protein, conserved
— Both
LPAL13_260023800 ⚠
microtubule-associated protein, putative
— Both
LPAL13_210020100 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— Both
LPAL13_350073800 ⚠
ubiquitin-protein ligase, putative
— Both
LPAL13_000013100
WD domain, G-beta repeat, putative
— Both
LPAL13_320012200
OSM3-like kinesin, putative
— OG6
LPAL13_300005600
MATH domain containing protein, putative
— Both
LPAL13_220010400
proteasome regulatory ATPase subunit 1, putat
— OG6
LPAL13_320008200
WD40 repeats, putative
— Both
LPAL13_220017400
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— Both
LPAL13_260015900 ⚠
Axonemal dynein light chain, putative
— Both
LPAL13_230017400
hypothetical protein, conserved
— Both
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— Both
LPAL13_220017100
i/6 autoantigen-like protein
— Both
LPAL13_200021100
hypothetical protein, conserved
— Both
LPAL13_270029900 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_260023700 ⚠
microtubule-associated protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.