LPAL13_000050500

Domain of unknown function (DUF3819)/CCR4-Not complex component, Not1, putative

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101511 OG7: OG7_0005420 101 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 101 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_120008500 CCR4-NOT transcription complex subunit 2, put	—	OG6 Tb927.10.1510 ↔ Tb927.6.850 OG6 TCSYLVIO_006963 ↔ TCSYLVIO_007990 OG6 LdBPK_120300.1 ↔ LdBPK_210880.1 OG7 Tb927.10.1510 ↔ Tb927.6.850 +2 more	Both
LPAL13_250021300 Not1 N-terminal domain, CCR4-Not complex comp	—	OG6 Tb927.10.1510 ↔ Tb927.3.1920 OG6 LdBPK_210880.1 ↔ LdBPK_251920.1 OG7 Tb927.10.1510 ↔ Tb927.3.1920 OG7 LdBPK_210880.1 ↔ LdBPK_251920.1	Both
LPAL13_220018900 CCR4 associated factor, putative	—	OG6 Tb927.10.1510 ↔ Tb927.6.600 OG6 LdBPK_210880.1 ↔ LdBPK_221480.1 OG7 Tb927.10.1510 ↔ Tb927.6.600 OG7 LdBPK_210880.1 ↔ LdBPK_221480.1	Both
LPAL13_200047500 cell differentiation protein-like protein	—	OG6 Tb927.10.1510 ↔ Tb927.4.410 OG6 LdBPK_210880.1 ↔ LdBPK_344180.1 OG7 Tb927.10.1510 ↔ Tb927.4.410 OG7 LdBPK_210880.1 ↔ LdBPK_344180.1	Both
LPAL13_270032400 ⚠ heat shock protein DNAJ, putative	—	OG6 LdBPK_210550.1 ↔ LdBPK_210880.1 OG7 LdBPK_210550.1 ↔ LdBPK_210880.1	Both
LPAL13_210009700 ⚠ DnaJ protein, putative	—	OG6 LdBPK_210550.1 ↔ LdBPK_210880.1 OG7 LdBPK_210550.1 ↔ LdBPK_210880.1	Both
LPAL13_270020900 hypothetical protein, conserved	—	OG6 Tb927.10.1510 ↔ Tb927.11.2030 OG7 Tb927.10.1510 ↔ Tb927.11.2030	Both
LPAL13_200014900 EF hand/EF-hand domain pair, putative	—	OG6 Tb927.10.1510 ↔ Tb927.4.3330 OG7 Tb927.10.1510 ↔ Tb927.4.3330	Both
LPAL13_230005000 hypothetical protein, conserved	—	OG6 Tb927.10.1510 ↔ Tb927.8.1960 OG7 Tb927.10.1510 ↔ Tb927.8.1960	Both
LPAL13_350071000 CCR4-NOT transcription complex subunit 10, pu	—	OG6 Tb927.10.1510 ↔ Tb927.10.8720 OG7 Tb927.10.1510 ↔ Tb927.10.8720	Both
LPAL13_150016400 ⚠ protein kinase, putative	—	OG6 LdBPK_151180.1 ↔ LdBPK_210880.1 OG7 LdBPK_151180.1 ↔ LdBPK_210880.1	Both
LPAL13_050008500 ⚠ structural maintenance of chromosome (SMC), p	—	OG6 LdBPK_050400.1 ↔ LdBPK_210880.1 OG7 LdBPK_050400.1 ↔ LdBPK_210880.1 OG7 LdBPK_210880.1 ↔ LdBPK_211580.1	Both
LPAL13_290030100 hypothetical protein, conserved	—	OG6 LdBPK_130340.1 ↔ LdBPK_210880.1 OG7 LdBPK_130340.1 ↔ LdBPK_210880.1	Both
LPAL13_120006100 ⚠ FYVE zinc finger containing protein, putative	—	OG6 LdBPK_120110.1 ↔ LdBPK_210880.1 OG7 LdBPK_120110.1 ↔ LdBPK_210880.1	Both
LPAL13_050013900 paraflagellar rod protein, putative	—	OG6 LdBPK_050920.1 ↔ LdBPK_210880.1 OG7 LdBPK_050920.1 ↔ LdBPK_210880.1	Both
LPAL13_070006200 ⚠ Sec7 domain containing protein, putative	—	OG6 LdBPK_070270.1 ↔ LdBPK_210880.1 OG7 LdBPK_070270.1 ↔ LdBPK_210880.1	Both
LPAL13_110011800 hypothetical protein, conserved	—	OG6 LdBPK_110830.1 ↔ LdBPK_210880.1 OG7 LdBPK_110830.1 ↔ LdBPK_210880.1	Both
LPAL13_350039000 ⚠ fibrillarin	—	OG6 LdBPK_190090.1 ↔ LdBPK_210880.1 OG7 LdBPK_190090.1 ↔ LdBPK_210880.1	Both
LPAL13_190009000 ⚠ fibrillarin, putative	—	OG6 LdBPK_190090.1 ↔ LdBPK_210880.1 OG7 LdBPK_190090.1 ↔ LdBPK_210880.1	Both
LPAL13_140012900 hypothetical protein, conserved	—	OG6 LdBPK_140850.1 ↔ LdBPK_210880.1 OG7 LdBPK_140850.1 ↔ LdBPK_210880.1	Both
LPAL13_000022500 WD domain, G-beta repeat, putative	—	OG6 LdBPK_190980.1 ↔ LdBPK_210880.1 OG7 LdBPK_190980.1 ↔ LdBPK_210880.1	Both
LPAL13_190016000 ⚠ CAP-Gly domain containing protein, putative	—	OG6 LdBPK_190890.1 ↔ LdBPK_210880.1 OG7 LdBPK_190890.1 ↔ LdBPK_210880.1	Both
LPAL13_350024400 ⚠ exoribonuclease 2, putative	—	OG6 LdBPK_060260.1 ↔ LdBPK_210880.1 OG7 LdBPK_060260.1 ↔ LdBPK_210880.1	Both
LPAL13_060007900 ⚠ 5'-3' exonuclease, putative	—	OG6 LdBPK_060260.1 ↔ LdBPK_210880.1 OG7 LdBPK_060260.1 ↔ LdBPK_210880.1	Both
LPAL13_070008100 ⚠ ubiquitin-protein ligase-like, putative	—	OG6 LdBPK_070440.1 ↔ LdBPK_210880.1 OG7 LdBPK_070440.1 ↔ LdBPK_210880.1	Both
LPAL13_210010300 Tetratricopeptide repeat, putative	—	OG6 LdBPK_210590.1 ↔ LdBPK_210880.1 OG7 LdBPK_210590.1 ↔ LdBPK_210880.1	Both
LPAL13_100016400 hypothetical protein, conserved	—	OG6 LdBPK_101140.1 ↔ LdBPK_210880.1 OG7 LdBPK_101140.1 ↔ LdBPK_210880.1	Both
LPAL13_040011400 Tetratricopeptide repeat/TPR repeat, putative	—	OG6 LdBPK_040540.1 ↔ LdBPK_210880.1 OG7 LdBPK_040540.1 ↔ LdBPK_210880.1	Both
LPAL13_110007800 mRNA cap guanine-N7 methyltransferase, putati	—	OG6 TCSYLVIO_001682 ↔ TCSYLVIO_007990 OG7 TCSYLVIO_001682 ↔ TCSYLVIO_007990	Both
LPAL13_020005900 ⚠ phosphatidylinositol kinase related protein,	—	OG6 LdBPK_020100.1 ↔ LdBPK_210880.1 OG7 LdBPK_020100.1 ↔ LdBPK_210880.1 OG7 LdBPK_210880.1 ↔ LdBPK_366580.1	Both
LPAL13_300010400 hypothetical protein, conserved	—	OG6 LdBPK_210880.1 ↔ LdBPK_300500.1 OG7 LdBPK_210880.1 ↔ LdBPK_300500.1	Both
LPAL13_290016400 hypothetical protein, conserved	—	OG6 LdBPK_210880.1 ↔ LdBPK_291270.1 OG7 LdBPK_210880.1 ↔ LdBPK_291270.1	Both
LPAL13_240026700 hypothetical protein, conserved	—	OG6 LdBPK_210880.1 ↔ LdBPK_242040.1 OG7 LdBPK_210880.1 ↔ LdBPK_242040.1	Both
LPAL13_260023800 ⚠ microtubule-associated protein, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_261950.1 OG7 LdBPK_210880.1 ↔ LdBPK_261950.1	Both
LPAL13_210020100 ⚠ RecF/RecN/SMC N terminal domain/SMC proteins	—	OG6 LdBPK_210880.1 ↔ LdBPK_211580.1 OG7 LdBPK_050400.1 ↔ LdBPK_210880.1 OG7 LdBPK_210880.1 ↔ LdBPK_211580.1	Both
LPAL13_350073800 ⚠ ubiquitin-protein ligase, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_366600.1 OG7 LdBPK_210880.1 ↔ LdBPK_366600.1	Both
LPAL13_000013100 WD domain, G-beta repeat, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_330300.1 OG7 LdBPK_210880.1 ↔ LdBPK_330300.1	Both
LPAL13_320012200 OSM3-like kinesin, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_320710.1	OG6
LPAL13_300005600 MATH domain containing protein, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_300050.1 OG7 LdBPK_210880.1 ↔ LdBPK_300050.1	Both
LPAL13_220010400 proteasome regulatory ATPase subunit 1, putat	—	OG6 LdBPK_210880.1 ↔ LdBPK_220440.1	OG6
LPAL13_320008200 WD40 repeats, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_320320.1 OG7 LdBPK_210880.1 ↔ LdBPK_320320.1	Both
LPAL13_220017400 ATP-dependent DEAD/H RNA helicase, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_221350.1	OG6
LPAL13_200047300 ⚠ phosphatidylinositol 3-kinase (tor2), putativ	—	OG6 LdBPK_210880.1 ↔ LdBPK_366580.1 OG7 LdBPK_020100.1 ↔ LdBPK_210880.1 OG7 LdBPK_210880.1 ↔ LdBPK_366580.1	Both
LPAL13_260015900 ⚠ Axonemal dynein light chain, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_261100.1 OG7 LdBPK_210880.1 ↔ LdBPK_261100.1	Both
LPAL13_230017400 hypothetical protein, conserved	—	OG6 LdBPK_210880.1 ↔ LdBPK_231090.1 OG7 LdBPK_210880.1 ↔ LdBPK_231090.1	Both
LPAL13_350073300 ⚠ target of rapamycin (TOR) kinase 1, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_366580.1 OG7 LdBPK_020100.1 ↔ LdBPK_210880.1 OG7 LdBPK_210880.1 ↔ LdBPK_366580.1	Both
LPAL13_220017100 i/6 autoantigen-like protein	—	OG6 LdBPK_210880.1 ↔ LdBPK_221310.1 OG7 LdBPK_210880.1 ↔ LdBPK_221310.1	Both
LPAL13_200021100 hypothetical protein, conserved	—	OG6 LdBPK_210880.1 ↔ LdBPK_341610.1 OG7 LdBPK_210880.1 ↔ LdBPK_341610.1	Both
LPAL13_270029900 ⚠ WD domain, G-beta repeat, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_272090.1 OG7 LdBPK_210880.1 ↔ LdBPK_272090.1	Both
LPAL13_260023700 ⚠ microtubule-associated protein, putative	—	OG6 LdBPK_210880.1 ↔ LdBPK_261950.1 OG7 LdBPK_210880.1 ↔ LdBPK_261950.1	Both

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