LPAL13_220017400

ATP-dependent DEAD/H RNA helicase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_126543 OG7: OG7_0000698 90 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 90 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_340038400
Putative death-receptor fusion protein (DUF24
— OG6
LPAL13_290016900
COPII coat assembly protein sec16, putative
— OG6
LPAL13_280007600
hypothetical protein, conserved
— OG6
LPAL13_230017400
hypothetical protein, conserved
— OG6
LPAL13_260015900
Axonemal dynein light chain, putative
— OG6
LPAL13_340037700
60S ribosomal subunit protein L31, putative
— OG6
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG6
LPAL13_250021300
Not1 N-terminal domain, CCR4-Not complex comp
— OG6
LPAL13_320008200
WD40 repeats, putative
— OG6
LPAL13_300005600
MATH domain containing protein, putative
— OG6
LPAL13_320012200
OSM3-like kinesin, putative
— OG6
LPAL13_350067500
Rab3 GTPase-activating protein regulatory sub
— OG6
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG6
LPAL13_000013100
WD domain, G-beta repeat, putative
— OG6
LPAL13_350073800
ubiquitin-protein ligase, putative
— OG6
LPAL13_350032000
hypothetical protein, conserved
— OG6
LPAL13_200006700
WD domain, G-beta repeat, putative
— OG6
LPAL13_280035500
Uncharacterized ACR, COG1678, putative
— OG6
LPAL13_330038300
hypothetical protein, conserved
— OG6
LPAL13_250020300
Clusterin-associated protein-1, putative
— OG6
LPAL13_300031300
Stabilization of polarity axis, putative
— OG6
LPAL13_260023800 ⚠
microtubule-associated protein, putative
— OG6
LPAL13_300038900
protein mkt1, putative
— OG6
LPAL13_330022300
Tetratricopeptide repeats, putative
— OG6
LPAL13_060007000
hypothetical protein, conserved
— OG6
LPAL13_090017700
AAA family ATPase, putative
— OG6
LPAL13_180017300
Protein of unknown function (DUF3648), putati
— OG6
LPAL13_220010400
proteasome regulatory ATPase subunit 1, putat
— OG6
LPAL13_010008900
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
LPAL13_120005000
translation initiation factor EIF-2b alpha su
— OG6
LPAL13_150014400
protein phosphatase 2A regulatory subunit, pu
— OG6
LPAL13_040008900
hypothetical protein, conserved
— OG6
LPAL13_160011000
ubiquitin hydrolase, putative
— OG6
LPAL13_350015700
hypothetical protein, conserved
— OG6
LPAL13_340021700
casein kinase II, putative
— OG6
LPAL13_320021100
Microtubule-binding protein MIP-T3, putative
— OG6
LPAL13_290014300
kinesin, putative
— OG6
LPAL13_290029300
serine/threonine-protein kinase Nek3, putativ
— OG6
LPAL13_270029900
WD domain, G-beta repeat, putative
— OG6
LPAL13_330034600
Unc104-like kinesin, putative
— OG6
LPAL13_260023700 ⚠
microtubule-associated protein, putative
— OG6
LPAL13_200021100
hypothetical protein, conserved
— OG6
LPAL13_300028300
Tetratricopeptide repeats, putative
— OG6
LPAL13_350071500
hypothetical protein, conserved
— OG6
LPAL13_350066300
hypothetical protein, conserved
— OG6
LPAL13_070006200
Sec7 domain containing protein, putative
— OG6
LPAL13_040011600
DENN (AEX-3) domain containing protein, putat
— OG6
LPAL13_070008100
ubiquitin-protein ligase-like, putative
— OG6
LPAL13_060007900 ⚠
5'-3' exonuclease, putative
— OG6
LPAL13_350024400 ⚠
exoribonuclease 2, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.