LPAL13_300028300

Tetratricopeptide repeats, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_147272 OG7: OG7_0043245 160 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 160 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_270012200 ⚠
replication factor C, subunit 4, putative
— OG7
LPAL13_150011400
hypothetical protein, conserved
— Both
LPAL13_270015100
parallel beta-helix repeat, putative
— Both
LPAL13_220017400
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LPAL13_000015500 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LPAL13_160011000 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_040008900
hypothetical protein, conserved
— Both
LPAL13_150014400
protein phosphatase 2A regulatory subunit, pu
— Both
LPAL13_230006100 ⚠
Beige/BEACH domain containing protein, putati
— Both
LPAL13_010008900 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LPAL13_180017300
Protein of unknown function (DUF3648), putati
— Both
LPAL13_130014600 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
LPAL13_250019000 ⚠
RNA-binding protein RBP10, putative
— Both
LPAL13_290029300
serine/threonine-protein kinase Nek3, putativ
— OG6
LPAL13_060007000
hypothetical protein, conserved
— Both
LPAL13_240011800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_210008900 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LPAL13_300017500 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_200059700 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_320021000 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LPAL13_110013800 ⚠
adaptin-related protein-like protein
— OG7
LPAL13_320013200 ⚠
cyclin 9, putative
— OG7
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LPAL13_240023600 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_000050300 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LPAL13_350079300 ⚠
beta-adaptin, putative
— OG7
LPAL13_060010600 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_170007300 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_200048300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_310006600 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_340037400 ⚠
replication factor C, subunit 3, putative
— OG7
LPAL13_350063900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_300030300 ⚠
replication factor C, subunit 2, putative
— OG7
LPAL13_330027400 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_350078800 ⚠
replication factor C, subunit 5, putative
— OG7
LPAL13_080012300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LPAL13_240015700 ⚠
replication factor C, subunit 1, putative
— OG7
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340048700 ⚠
predicted zinc finger protein
— OG7
LPAL13_350019500 ⚠
adenylate kinase, putative
— OG7
LPAL13_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LPAL13_350023700 ⚠
neurobeachin/beige protein, putative
— OG7
LPAL13_200007500 ⚠
RNA polymerase ii largest subunit
— OG7
LPAL13_230026800 ⚠
neutral sphingomyelinase activation associate
— OG7
LPAL13_190016400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_090017200 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.