LPAL13_270012200

replication factor C, subunit 4, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100321 OG7: OG7_0001167 128 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 128 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_090020600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280032900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_260019500 ⚠
farnesyltransferase beta subunit
— OG7
LPAL13_340036900 ⚠
RNA-binding protein, putative
— OG7
LPAL13_290027300 ⚠
protein kinase, putative
— OG7
LPAL13_170010500 ⚠
ATPase family associated with various cellula
— OG7
LPAL13_350031800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300013000 ⚠
co-chaperone GrpE, putative
— OG7
LPAL13_330033500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340029100 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_330008700 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LPAL13_190020800 ⚠
eukaryotic translation initiation factor-like
— OG7
LPAL13_260016900 ⚠
Leucine Rich Repeat/Leucine rich repeat, puta
— OG7
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LPAL13_200044100 ⚠
geranylgeranyltransferase, putative
— OG7
LPAL13_340014200 ⚠
hypothetical protein
— OG7
LPAL13_180016100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200023700 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LPAL13_190007500 ⚠
protein kinase, putative
— OG7
LPAL13_080007000 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_000018400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280031800 ⚠
WW domain containing protein, putative
— OG7
LPAL13_120009700 ⚠
WW domain containing protein, putative
— OG7
LPAL13_170017400 ⚠
WW domain containing protein, putative
— OG7
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_200044400 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_130009200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000033700 ⚠
Beta-lactamase superfamily domain containing
— OG7
LPAL13_150010200 ⚠
ecotin, putative
— OG7
LPAL13_110013200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_190015000 ⚠
Suppressor-of-White-APricot splicing regulato
— OG7
LPAL13_230008800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_230011800 ⚠
5'-3' exonuclease XRNC, putative
— OG7
LPAL13_080006000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000018300 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LPAL13_090016500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_120007400 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LPAL13_030008900 ⚠
TLD domain protein, conserved
— OG7
LPAL13_060015300 ⚠
TLD, putative
— OG7
LPAL13_350026400 ⚠
TLD, putative
— OG7
LPAL13_200056700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_080009200 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_150008400 ⚠
ecotin, putative
— OG7
LPAL13_150010300 ⚠
ecotin, putative
— OG7
LPAL13_180009400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_150011000 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.