LPAL13_240027300

tubulin folding cofactor D, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102599 OG7: OG7_0006853 206 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 206 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_350074100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_200051800 ⚠
developmentally regulated phosphoprotein-like
— Both
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— Both
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— Both
LPAL13_080009200
WD domain, G-beta repeat, putative
— Both
LPAL13_180015400 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— +2 more Both
LPAL13_180015500 ⚠
Aminoacyl-tRNA editing domain containing prot
— +2 more Both
LPAL13_000018300
phenylalanyl-tRNA synthetase, putative
— Both
LPAL13_240005000 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_200042700 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— +1 more Both
LPAL13_300011100
hypothetical protein, conserved
— Both
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_120007400
cysteinyl-tRNA synthetase, putative
— Both
LPAL13_200006800 ⚠
tRNA pseudouridine synthase, putative
— Both
LPAL13_270023300 ⚠
eukaryotic translation initiation factor eIF-
— OG7
LPAL13_350058500 ⚠
Leucine rich repeat, putative
— OG7
LPAL13_340048700 ⚠
predicted zinc finger protein
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_170010500 ⚠
ATPase family associated with various cellula
— OG7
LPAL13_270012200 ⚠
replication factor C, subunit 4, putative
— OG7
LPAL13_200059300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350078800 ⚠
replication factor C, subunit 5, putative
— OG7
LPAL13_300030300 ⚠
replication factor C, subunit 2, putative
— OG7
LPAL13_340037400 ⚠
replication factor C, subunit 3, putative
— OG7
LPAL13_130012600
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LPAL13_100018300 ⚠
hypothetical protein, conserved
— Both
LPAL13_350079300 ⚠
beta-adaptin, putative
— Both
LPAL13_200060500 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_240026100
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LPAL13_180005800 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
LPAL13_180016100
hypothetical protein, conserved
— Both
LPAL13_280035900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_340018800
threonyl-tRNA synthetase, putative
— Both
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_350039300
ATP synthase, putative
— Both
LPAL13_340038500
hypothetical protein, conserved
— Both
LPAL13_340034100 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LPAL13_200044700
GRIP domain containing protein, putative
— Both
LPAL13_280036500 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_150008200
ribonucleoprotein p18, mitochondrial precurso
— Both
LPAL13_270020700
hypothetical protein, conserved
— OG7
LPAL13_320037000 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_200046600
nucleolar protein family a, putative
— Both
LPAL13_200060300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_290011700 ⚠
heat shock protein 90, putative
— +2 more Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.