LPAL13_270023300

eukaryotic translation initiation factor eIF-4E, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100627 OG7: OG7_0002303 212 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 212 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_330036600 ⚠
translation initiation factor IF-2, putative
— OG7
LPAL13_280020500 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_280020800 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LPAL13_020006300 ⚠
Vps51/Vps67, putative
— OG7
LPAL13_250016600 ⚠
dehydrogenase-like protein
— OG7
LPAL13_130009200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_220008100 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LPAL13_190021500 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LPAL13_170017400 ⚠
WW domain containing protein, putative
— OG7
LPAL13_120009700 ⚠
WW domain containing protein, putative
— OG7
LPAL13_280031800 ⚠
WW domain containing protein, putative
— OG7
LPAL13_260027700 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_150009500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200043500 ⚠
adaptor gamma-1 chain, putative
— OG7
LPAL13_200021000 ⚠
Protein of unknown function (DUF3808), putati
— OG7
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LPAL13_350023700 ⚠
neurobeachin/beige protein, putative
— OG7
LPAL13_300011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350023800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_230026800 ⚠
neutral sphingomyelinase activation associate
— OG7
LPAL13_330033500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_350063100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_330037000 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_320024200 ⚠
Phosphatidylethanolamine-binding protein, put
— OG7
LPAL13_320015600 ⚠
Vps23 core domain containing protein, putativ
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_180015400 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LPAL13_350078800 ⚠
replication factor C, subunit 5, putative
— OG7
LPAL13_240015700 ⚠
replication factor C, subunit 1, putative
— OG7
LPAL13_200059300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270012200 ⚠
replication factor C, subunit 4, putative
— OG7
LPAL13_170010500 ⚠
ATPase family associated with various cellula
— OG7
LPAL13_310035400 ⚠
aldehyde reductase, putative
— OG7
LPAL13_270032500 ⚠
aldo-keto reductase-like protein
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_240027300 ⚠
tubulin folding cofactor D, putative
— OG7
LPAL13_350013400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_230006100 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LPAL13_340054400 ⚠
breast cancer carboxy-terminal domain contain
— OG7
LPAL13_070005500 ⚠
alpha-adaptin-like protein
— OG7
LPAL13_200007600 ⚠
Conserved oligomeric complex COG6, putative
— OG7
LPAL13_330026700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350006400 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LPAL13_240005100 ⚠
clathrin coat assembly protein, putative
— OG7
LPAL13_070013700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.