LPAL13_220014600

translation initiation factor IF-2, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100987 OG7: OG7_0005015 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_240017800 ⚠
hypothetical protein, conserved
— Both
LPAL13_220006600 ⚠
hypothetical protein, conserved
— Both
LPAL13_110009500 ⚠
hypothetical protein, conserved
— Both
LPAL13_220008000 ⚠
hypothetical protein, conserved
— Both
LPAL13_240008100 ⚠
Ring finger containing protein, putative
— Both
LPAL13_180005200 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LPAL13_200065400 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LPAL13_350028700 ⚠
NOL1/NOP2/sun family, putative
— Both
LPAL13_270010200 ⚠
nucleoporin, putative
— Both
LPAL13_340052000 ⚠
Cysteine-rich motif following a subset of SET
— Both
LPAL13_160016500 ⚠
hypothetical protein, conserved
— Both
LPAL13_220017900 ⚠
alanyl-tRNA synthetase, putative
— Both
LPAL13_280031500 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LPAL13_000050400 ⚠
methionyl-tRNA synthetase
— Both
LPAL13_180011700
cyclosporin 16, putative
— OG6
LPAL13_060014700 ⚠
acyl-coenzyme a dehydrogenase, putative
— Both
LPAL13_230006000 ⚠
GDP-mannose pyrophosphorylase
— Both
LPAL13_200051400 ⚠
deoxyhypusine synthase, putative
— Both
LPAL13_140009600 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LPAL13_290005600 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
LPAL13_200060000 ⚠
Pre-mRNA-splicing factor 38, putative
— Both
LPAL13_280035500 ⚠
Uncharacterized ACR, COG1678, putative
— Both
LPAL13_270008900
protein kinase, putative
— OG6
LPAL13_290023500 ⚠
UDP-glucose:Glycoprotein Glucosyltransferase,
— Both
LPAL13_200041100 ⚠
hypothetical protein, conserved
— Both
LPAL13_300016800 ⚠
importin alpha, putative
— Both
LPAL13_200024400 ⚠
Endonuclease/Exonuclease/phosphatase family,
— Both
LPAL13_340057100 ⚠
hypothetical protein, conserved
— Both
LPAL13_300037600 ⚠
UV excision repair RAD23-like protein
— Both
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— Both
LPAL13_270032300 ⚠
TPR-repeat protein, putative
— OG6
LPAL13_260008000 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
LPAL13_350066100 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LPAL13_290020600 ⚠
XPC-binding domain/UBA/TS-N domain containing
— Both
LPAL13_340008400 ⚠
hypothetical protein, conserved
— Both
LPAL13_300027100 ⚠
hypothetical protein, conserved
— Both
LPAL13_060014500 ⚠
acyl-coenzyme a dehydrogenase, putative
— Both
LPAL13_330010700 ⚠
hypothetical protein, conserved
— Both
LPAL13_140019600 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LPAL13_130014400 ⚠
leucyl-tRNA synthetase, putative
— Both
LPAL13_000036300 ⚠
ABC transport system ATP-binding protein, put
— Both
LPAL13_350031400 ⚠
dipeptidyl-peptidase 8-like serine peptidase,
— Both
LPAL13_340031800 ⚠
acyl-CoA dehydrogenase, putative
— Both
LPAL13_350070700 ⚠
disgorgin, putative
— Both
LPAL13_250006900 ⚠
cleavage and polyadenylation specificity fact
— Both
LPAL13_130013500 ⚠
hypothetical protein
— OG6
LPAL13_050012700 ⚠
hypothetical protein, conserved
— Both
LPAL13_140019200 ⚠
inositol-3-phosphate synthase
— Both
LPAL13_300035800 ⚠
valyl-tRNA synthetase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.