LPAL13_220014600

translation initiation factor IF-2, putative

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100987 OG7: OG7_0005015 101 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 101 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_240017800 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001462 ↔ TCSYLVIO_001768 OG7 TCSYLVIO_001462 ↔ TCSYLVIO_001768	Both
LPAL13_220006600 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001150 ↔ TCSYLVIO_001768 OG7 TCSYLVIO_001150 ↔ TCSYLVIO_001768	Both
LPAL13_110009500 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001678 ↔ TCSYLVIO_001768 OG7 TCSYLVIO_001678 ↔ TCSYLVIO_001768	Both
LPAL13_220008000 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001161 ↔ TCSYLVIO_001768 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_001768	Both
LPAL13_240008100 ⚠ Ring finger containing protein, putative	—	OG6 TCSYLVIO_001546 ↔ TCSYLVIO_001768 OG7 TCSYLVIO_001546 ↔ TCSYLVIO_001768	Both
LPAL13_180005200 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_001768 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_001768	Both
LPAL13_200065400 ⚠ tRNA (Uracil-5-)-methyltransferase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_008409 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_008409	Both
LPAL13_350028700 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004998	Both
LPAL13_270010200 ⚠ nucleoporin, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007387 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007387	Both
LPAL13_340052000 ⚠ Cysteine-rich motif following a subset of SET	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_005710	Both
LPAL13_160016500 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_006128 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_006128	Both
LPAL13_220017900 ⚠ alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_001889 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_001889	Both
LPAL13_280031500 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_010621	Both
LPAL13_170008400 ⚠ Dihydrouridine synthase (Dus), putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_009102	Both
LPAL13_000050400 ⚠ methionyl-tRNA synthetase	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007991	Both
LPAL13_180011700 cyclosporin 16, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_006217	OG6
LPAL13_060014700 ⚠ acyl-coenzyme a dehydrogenase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_001861 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_001861	Both
LPAL13_230006000 ⚠ GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007603	Both
LPAL13_200051400 ⚠ deoxyhypusine synthase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
LPAL13_140009600 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_010327	Both
LPAL13_290005600 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_010724	Both
LPAL13_200060000 ⚠ Pre-mRNA-splicing factor 38, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007337 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007337	Both
LPAL13_280035500 ⚠ Uncharacterized ACR, COG1678, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007619 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007619	Both
LPAL13_270008900 protein kinase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_005149	OG6
LPAL13_290023500 ⚠ UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004363 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004363	Both
LPAL13_200041100 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003737 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003737	Both
LPAL13_300016800 ⚠ importin alpha, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003173 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003173	Both
LPAL13_200024400 ⚠ Endonuclease/Exonuclease/phosphatase family,	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003876 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003876	Both
LPAL13_340057100 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_005652 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_005652	Both
LPAL13_300037600 ⚠ UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003361 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003361	Both
LPAL13_280009900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_002526 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_002525 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_002526 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_002525	Both
LPAL13_270032300 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003496	OG6
LPAL13_260008000 ⚠ C-1-tetrahydrofolate synthase, cytoplasmic, p	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003291	OG6
LPAL13_350066100 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004705	Both
LPAL13_290020600 ⚠ XPC-binding domain/UBA/TS-N domain containing	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004322 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004322	Both
LPAL13_340008400 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_005080 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_005080	Both
LPAL13_300027100 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003268 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003268	Both
LPAL13_060014500 ⚠ acyl-coenzyme a dehydrogenase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_001861 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_001861	Both
LPAL13_330010700 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004859 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004859	Both
LPAL13_140019600 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_010624	Both
LPAL13_130014400 ⚠ leucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003028	Both
LPAL13_000036300 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_006012 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_006012	Both
LPAL13_350031400 ⚠ dipeptidyl-peptidase 8-like serine peptidase,	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007536 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007536	Both
LPAL13_340031800 ⚠ acyl-CoA dehydrogenase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_005872 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_005872	Both
LPAL13_350070700 ⚠ disgorgin, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004663 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004663	Both
LPAL13_250006900 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_005414 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_005414	Both
LPAL13_130013500 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003173	OG6
LPAL13_050012700 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_001973 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_001973	Both
LPAL13_140019200 ⚠ inositol-3-phosphate synthase	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007453	Both
LPAL13_300035800 ⚠ valyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003345 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003345	Both

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