LPAL13_140019200

inositol-3-phosphate synthase

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100830 OG7: OG7_0006574 189 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 189 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_040008700 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	OG7
LPAL13_110013900 pyruvate phosphate dikinase, putative	—	OG6 LdBPK_111000.1 ↔ LdBPK_141450.1 OG6 Tb927.10.7110 ↔ Tb927.11.6280 OG7 Tb927.10.7110 ↔ Tb927.11.6280 OG7 LdBPK_111000.1 ↔ LdBPK_141450.1	Both
LPAL13_330008100 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG6 LdBPK_141450.1 ↔ LdBPK_330340.1 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LPAL13_000036300 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LPAL13_340052000 Cysteine-rich motif following a subset of SET	—	OG6 TCSYLVIO_005710 ↔ TCSYLVIO_007453 OG6 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007453	Both
LPAL13_030006400 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	OG7
LPAL13_280009900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 +1 more	Both
LPAL13_230006000 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
LPAL13_250014900 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_007401 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LPAL13_280008700 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	Both
LPAL13_330020900 ⚠ protein kinase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LPAL13_290023900 protein kinase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_292260.1 OG7 LdBPK_141450.1 ↔ LdBPK_292260.1	Both
LPAL13_290023000 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_141450.1	OG7
LPAL13_120007700 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_141450.1 OG7 LdBPK_120105.1 ↔ LdBPK_141450.1	Both
LPAL13_030013300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LPAL13_190005800 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LPAL13_320048400 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007453	Both
LPAL13_350066100 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007453	Both
LPAL13_050012700 hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007453	Both
LPAL13_220017900 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007453	Both
LPAL13_250006900 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007453	Both
LPAL13_350005400 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LPAL13_270032300 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LPAL13_290023500 UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007453	Both
LPAL13_290027900 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LPAL13_350028700 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LPAL13_340008900 hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_007453	Both
LPAL13_220014600 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007453	Both
LPAL13_180006000 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_006140 ↔ TCSYLVIO_007453 OG6 TCSYLVIO_006141 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007453	Both
LPAL13_340016300 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_141450.1 ↔ LdBPK_241120.1	OG6
LPAL13_300010200 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_300480.1 OG7 LdBPK_141450.1 ↔ LdBPK_300480.1	Both
LPAL13_250016800 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_251070.1 OG7 LdBPK_141450.1 ↔ LdBPK_251070.1	Both
LPAL13_150011000 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_150690.1 OG7 LdBPK_141450.1 ↔ LdBPK_150690.1	Both
LPAL13_160007400 ⚠ Met-10+ like-protein, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_160320.1 OG7 LdBPK_141450.1 ↔ LdBPK_160320.1	Both
LPAL13_310017200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LPAL13_300035000 tRNA (Guanine-1)-methyltransferase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_303110.1 OG7 LdBPK_141450.1 ↔ LdBPK_303110.1	Both
LPAL13_200020700 EAP30/Vps36 family, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_341570.1 OG7 LdBPK_141450.1 ↔ LdBPK_341570.1	Both
LPAL13_200017100 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_341230.1 OG7 LdBPK_141450.1 ↔ LdBPK_341230.1	Both
LPAL13_170015300 Phosphorylated CTD interacting factor 1 WW do	—	OG6 LdBPK_141450.1 ↔ LdBPK_171050.1 OG7 LdBPK_141450.1 ↔ LdBPK_171050.1	Both
LPAL13_230018400 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_231180.1 OG7 LdBPK_141450.1 ↔ LdBPK_231180.1	Both
LPAL13_200017200 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_341230.1 OG7 LdBPK_141450.1 ↔ LdBPK_341230.1	Both
LPAL13_340012200 proteasome activator protein pa26, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_350770.1 OG7 LdBPK_141450.1 ↔ LdBPK_350770.1	Both
LPAL13_240016800 ⚠ pre-mRNA splicing factor, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_241120.1	OG6
LPAL13_350036400 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_141450.1 ↔ LdBPK_241120.1	OG6
LPAL13_170011700 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_141450.1	OG7
LPAL13_330034700 ⚠ aminopeptidase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_141450.1 OG7 LdBPK_110640.1 ↔ LdBPK_141450.1 OG7 LdBPK_141450.1 ↔ LdBPK_332700.1	Both
LPAL13_240006100 ankyrin/TPR repeat protein	—	OG6 LdBPK_141450.1 ↔ LdBPK_240130.1	OG6
LPAL13_350072300 flagellum transition zone component, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_366480.1 OG7 LdBPK_141450.1 ↔ LdBPK_366480.1	Both
LPAL13_200065800 ⚠ hypothetical protein	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LPAL13_200044400 ⚠ ubiquitin hydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_343890.1 OG7 LdBPK_141450.1 ↔ LdBPK_343890.1	Both

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