LPAL13_340052000

Cysteine-rich motif following a subset of SET domains/SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain containing protein, putative

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_108008 OG7: OG7_0013020 198 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 198 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_250014900 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_005710 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007401 OG7 LdBPK_331490.1 ↔ LdBPK_354620.1	Both
LPAL13_040008700 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005710 OG7 LdBPK_280470.1 ↔ LdBPK_354620.1	OG7
LPAL13_140019200 inositol-3-phosphate synthase	—	OG6 TCSYLVIO_005710 ↔ TCSYLVIO_007453 OG6 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007453	Both
LPAL13_280009900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_005710 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005710 +1 more	Both
LPAL13_330020900 ⚠ protein kinase, putative	—	OG6 LdBPK_331490.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007401 OG7 LdBPK_331490.1 ↔ LdBPK_354620.1	Both
LPAL13_280008700 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_280470.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005710 OG7 LdBPK_280470.1 ↔ LdBPK_354620.1	Both
LPAL13_200065800 ⚠ hypothetical protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LPAL13_030005400 ⚠ Met-10+ like-protein, putative	—	OG7 LdBPK_160320.1 ↔ LdBPK_354620.1	OG7
LPAL13_330033000 ⚠ ras-like small GTPases, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_354620.1	OG7
LPAL13_260018500 ⚠ guanine nucleotide-binding protein-like prote	—	OG7 LdBPK_050200.1 ↔ LdBPK_354620.1	OG7
LPAL13_340058600 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_354620.1	OG7
LPAL13_050009200 ⚠ GTPase, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_354620.1	OG7
LPAL13_270024400 ⚠ zinc finger containing protein, putative	—	OG7 LdBPK_271580.1 ↔ LdBPK_354620.1	OG7
LPAL13_200037300 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_005710	OG7
LPAL13_170011400 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_354620.1	OG7
LPAL13_200028600 ⚠ acyl-CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_354620.1	OG7
LPAL13_170011700 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_354620.1	OG7
LPAL13_110015000 ⚠ eukaryotic release factor 3, putative	—	OG7 LdBPK_354220.1 ↔ LdBPK_354620.1	OG7
LPAL13_170005000 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_354220.1 ↔ LdBPK_354620.1	OG7
LPAL13_290023000 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_354620.1	OG7
LPAL13_120007700 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_354620.1 OG7 LdBPK_120105.1 ↔ LdBPK_354620.1	Both
LPAL13_200067100 conserved protein, unknown function	—	OG6 LdBPK_200770.1 ↔ LdBPK_354620.1 OG7 LdBPK_200770.1 ↔ LdBPK_354620.1	Both
LPAL13_210022200 NIMA-related kinase, putative	—	OG6 LdBPK_211870.1 ↔ LdBPK_354620.1	OG6
LPAL13_350072300 flagellum transition zone component, putative	—	OG6 LdBPK_354620.1 ↔ LdBPK_366480.1 OG7 LdBPK_354620.1 ↔ LdBPK_366480.1	Both
LPAL13_030013300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005710	Both
LPAL13_190005800 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005710	Both
LPAL13_320048400 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_005710	Both
LPAL13_270028800 ⚠ ribonucleoside-diphosphate reductase small ch	—	OG6 LdBPK_221110.1 ↔ LdBPK_354620.1 OG7 LdBPK_221110.1 ↔ LdBPK_354620.1	Both
LPAL13_330027100 Ribosome assembly protein rrb1, putative	—	OG6 LdBPK_332020.1 ↔ LdBPK_354620.1 OG7 LdBPK_332020.1 ↔ LdBPK_354620.1	Both
LPAL13_340008900 hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_005710	Both
LPAL13_350028700 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_005710	Both
LPAL13_290027900 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_005710	Both
LPAL13_290023500 UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_005710	Both
LPAL13_160007400 ⚠ Met-10+ like-protein, putative	—	OG6 LdBPK_160320.1 ↔ LdBPK_354620.1 OG7 LdBPK_160320.1 ↔ LdBPK_354620.1	Both
LPAL13_340016300 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_241120.1 ↔ LdBPK_354620.1	OG6
LPAL13_350036400 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_241120.1 ↔ LdBPK_354620.1	OG6
LPAL13_240016800 ⚠ pre-mRNA splicing factor, putative	—	OG6 LdBPK_241120.1 ↔ LdBPK_354620.1	OG6
LPAL13_270032300 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_005710	OG6
LPAL13_350005400 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_005710	OG6
LPAL13_200020700 EAP30/Vps36 family, putative	—	OG6 LdBPK_341570.1 ↔ LdBPK_354620.1 OG7 LdBPK_341570.1 ↔ LdBPK_354620.1	Both
LPAL13_350066100 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005710	Both
LPAL13_310017200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LPAL13_200065900 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LPAL13_300019600 ⚠ hypothetical protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LPAL13_300019500 ⚠ hypothetical protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LPAL13_300019400 ⚠ Peptidase family M20/M25/M40, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LPAL13_220017900 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_005710	Both
LPAL13_220015100 ⚠ ribonucleoside-diphosphate reductase small ch	—	OG6 LdBPK_221110.1 ↔ LdBPK_354620.1 OG7 LdBPK_221110.1 ↔ LdBPK_354620.1	Both
LPAL13_250006900 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_005710	Both
LPAL13_070008900 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 LdBPK_353150.1 ↔ LdBPK_354620.1 OG7 LdBPK_282220.1 ↔ LdBPK_354620.1	OG7

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