LPAL13_250006900

cleavage and polyadenylation specificity factor, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_103283 OG7: OG7_0002417 152 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 152 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_200037300 ⚠
cleavage and polyadenylation specificity fact
— Both
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340052000 ⚠
Cysteine-rich motif following a subset of SET
— Both
LPAL13_280031500 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LPAL13_000050400 ⚠
methionyl-tRNA synthetase
— Both
LPAL13_180011700
cyclosporin 16, putative
— OG6
LPAL13_230006000 ⚠
GDP-mannose pyrophosphorylase
— Both
LPAL13_140009600 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LPAL13_290005600 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
LPAL13_200060000 ⚠
Pre-mRNA-splicing factor 38, putative
— Both
LPAL13_140019600 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LPAL13_000036300 ⚠
ABC transport system ATP-binding protein, put
— Both
LPAL13_350031400 ⚠
dipeptidyl-peptidase 8-like serine peptidase,
— Both
LPAL13_340031800 ⚠
acyl-CoA dehydrogenase, putative
— Both
LPAL13_140019200 ⚠
inositol-3-phosphate synthase
— Both
LPAL13_180006000 ⚠
alpha glucosidase II subunit, putative
— Both
LPAL13_250024300 ⚠
hypothetical protein, conserved
— Both
LPAL13_250014900 ⚠
protein kinase, putative
— Both
LPAL13_140018600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LPAL13_350006200 ⚠
PUB domain containing protein, putative
— Both
LPAL13_250027500 ⚠
hypothetical protein, conserved
— Both
LPAL13_220017900 ⚠
alanyl-tRNA synthetase, putative
— Both
LPAL13_120010700 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LPAL13_050012700 ⚠
hypothetical protein, conserved
— Both
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— Both
LPAL13_240015100 ⚠
hypothetical protein, conserved
— Both
LPAL13_350066100 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LPAL13_320048400 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— Both
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_090017700 ⚠
AAA family ATPase, putative
— Both
LPAL13_280008700 ⚠
rrp44p homologue, putative
— OG7
LPAL13_040008700 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LPAL13_200020000 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LPAL13_090014400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_000049800 ⚠
hypothetical protein
— OG7
LPAL13_160015700 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LPAL13_340034200 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_340031100 ⚠
ankyrin repeat protein, putative
— OG7
LPAL13_330006500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_290015500 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LPAL13_040011100 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LPAL13_300037200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_000009600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_160020600 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_200061200 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LPAL13_200031200 ⚠
regulatory subunit of protein kinase a-like p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.