LPAL13_300035800

valyl-tRNA synthetase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100292 OG7: OG7_0003490 119 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 119 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_300011800
histidyl-tRNA synthetase, putative
— Both
LPAL13_130014400
leucyl-tRNA synthetase, putative
— Both
LPAL13_000050400
methionyl-tRNA synthetase
— Both
LPAL13_220009500 ⚠
Putative tRNA binding domain containing prote
— OG7
LPAL13_160015700 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LPAL13_140019600 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LPAL13_040008700 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LPAL13_260008000 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
LPAL13_300029900 ⚠
formate--tetrahydrofolate ligase
— Both
LPAL13_260014500
Glucosidase II beta subunit-like protein, put
— Both
LPAL13_110009500
hypothetical protein, conserved
— Both
LPAL13_300039700
S-adenosylmethionine synthetase
— Both
LPAL13_180015500 ⚠
Aminoacyl-tRNA editing domain containing prot
— Both
LPAL13_180015400 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LPAL13_310031700
calreticulin, putative
— Both
LPAL13_060015400
glucosamine-fructose-6-phosphate aminotransfe
— Both
LPAL13_220008000
hypothetical protein, conserved
— Both
LPAL13_180005200 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LPAL13_220010600
Uncharacterised protein family UPF0066, putat
— Both
LPAL13_220014600 ⚠
translation initiation factor IF-2, putative
— Both
LPAL13_180014100 ⚠
protein kinase A catalytic subunit
— OG6
LPAL13_330029900
hypothetical protein, conserved
— Both
LPAL13_340046100 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LPAL13_320031300
hypothetical protein, conserved
— Both
LPAL13_200044400 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_270015500
WD40 repeats, putative
— Both
LPAL13_320037400
nucleoside diphosphate kinase b
— Both
LPAL13_220017900
alanyl-tRNA synthetase, putative
— Both
LPAL13_050012700
hypothetical protein, conserved
— Both
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— Both
LPAL13_320048400
Gar1/Naf1 RNA binding region containing prote
— Both
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— Both
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_200017000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_240021700 ⚠
translation initiation factor IF-2, putative
— OG7
LPAL13_330020900 ⚠
protein kinase, putative
— OG7
LPAL13_230008600 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LPAL13_180014400 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LPAL13_210005200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300012600 ⚠
nuclear movement protein, putative
— OG7
LPAL13_200037300 ⚠
cleavage and polyadenylation specificity fact
— OG7
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_350070800 ⚠
rab-like GTPase activating protein, putative
— OG7
LPAL13_310024900 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LPAL13_030006400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LPAL13_330008100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LPAL13_210005300 ⚠
ALIX V-shaped domain binding to HIV, putative
— OG7
LPAL13_340034200 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.