LPAL13_300039700

S-adenosylmethionine synthetase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100388 OG7: OG7_0003674 37 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 37 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_000009500 ⚠
fumarate hydratase, putative
— Both
LPAL13_010009400 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LPAL13_150019600
proliferative cell nuclear antigen (PCNA), pu
— Both
LPAL13_340053900 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— +1 more Both
LPAL13_140006100 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
LPAL13_010010000 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LPAL13_030007000 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LPAL13_010010100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LPAL13_240008300 ⚠
fumarate hydratase, putative
— Both
LPAL13_240027700
transketolase
— Both
LPAL13_120010000
glucose-6-phosphate isomerase
— Both
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_200017000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_300037000 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LPAL13_310024900 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LPAL13_010006000 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LPAL13_300021900 ⚠
queuine tRNA-ribosyltransferase, putative
— OG7
LPAL13_350061500 ⚠
aldehyde dehydrogenase, putative
— OG7
LPAL13_280035900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_130015300
adenylosuccinate synthetase, putative
— Both
LPAL13_300033900 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LPAL13_270005600 ⚠
tRNA-guanine family transglycosylase, putativ
— Both
LPAL13_270016300
isovaleryl-coA dehydrogenase, putative
— Both
LPAL13_280036000 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_260017100 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_280018900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_280036500 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_300033200 ⚠
aldehyde dehydrogenase, putative
— Both
LPAL13_190006800
NGG1 interacting factor 3-like protein
— Both
LPAL13_050008100
trypanothione reductase
— Both
LPAL13_300035800
valyl-tRNA synthetase, putative
— Both
LPAL13_290013000
guanine deaminase, putative
— Both
LPAL13_120010900
alanine aminotransferase
— Both
LPAL13_340005000
pyruvate kinase
— Both
LPAL13_150019500 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LPAL13_180018500 ⚠
nonspecific nucleoside hydrolase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.