LPAL13_040010400

cysteine peptidase, Clan CA, family C2, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_127587 OG7: OG7_0001161 131 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 131 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_110010200 ⚠
aminopeptidase, putative
— OG6
LPAL13_080007000 ⚠
ubiquitin-activating enzyme-like protein
— OG6
LPAL13_340034100 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG6
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— OG6
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— OG6
LPAL13_300019500 ⚠
hypothetical protein
— OG6
LPAL13_250022700 ⚠
hypothetical protein, conserved
— OG6
LPAL13_330027100 ⚠
Ribosome assembly protein rrb1, putative
— OG6
LPAL13_130007400 ⚠
flagellar radial spoke protein, putative
— OG6
LPAL13_320037000 ⚠
ubiquitin hydrolase, putative
— OG6
LPAL13_300013500 ⚠
Armadillo/beta-catenin-like repeats, putative
— OG6
LPAL13_280036000 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_260017100 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_280018900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_280036500 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_280035900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_230024100 ⚠
Inositol hexakisphosphate, putative
— OG6
LPAL13_280014100 ⚠
RNA binding protein rbp16, putative
— OG6
LPAL13_240008100 ⚠
Ring finger containing protein, putative
— OG6
LPAL13_300031300 ⚠
Stabilization of polarity axis, putative
— OG6
LPAL13_280035500 ⚠
Uncharacterized ACR, COG1678, putative
— OG6
LPAL13_270027700 ⚠
protein kinase-like protein
— OG6
LPAL13_340038400 ⚠
Putative death-receptor fusion protein (DUF24
— OG6
LPAL13_350067500 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG6
LPAL13_350066300 ⚠
hypothetical protein, conserved
— OG6
LPAL13_240018300 ⚠
hypothetical protein, conserved
— OG6
LPAL13_350015700 ⚠
hypothetical protein, conserved
— OG6
LPAL13_050014900 ⚠
MORN repeat, putative
— OG6
LPAL13_220010600 ⚠
Uncharacterised protein family UPF0066, putat
— OG6
LPAL13_150008200 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG6
LPAL13_010005200 ⚠
DNA-damage inducible protein DDI1-like protei
— OG6
LPAL13_340005000 ⚠
pyruvate kinase
— OG6
LPAL13_240026100 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG6
LPAL13_320007200 ⚠
Histone chaperone Rttp106-like, putative
— OG6
LPAL13_300019400 ⚠
Peptidase family M20/M25/M40, putative
— OG6
LPAL13_250026100 ⚠
Leucine Rich repeats (2 copies), putative
— OG6
LPAL13_150020100 ⚠
cAMP specific phosphodiesterase, putative
— OG6
LPAL13_150020000 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG6
LPAL13_000037600 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG6
LPAL13_060013800 ⚠
hypothetical protein, conserved
— OG6
LPAL13_260023300 ⚠
hypothetical protein, conserved
— OG6
LPAL13_100018300 ⚠
hypothetical protein, conserved
— OG6
LPAL13_090007200 ⚠
heat shock protein HslVU, ATPase subunit HslU
— OG6
LPAL13_090012900 ⚠
ubiquitin ligase, putative
— OG6
LPAL13_150015400 ⚠
glutamate dehydrogenase
— OG6
LPAL13_240027300 ⚠
tubulin folding cofactor D, putative
— OG6
LPAL13_300011100 ⚠
hypothetical protein, conserved
— OG6
LPAL13_130012600 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG6
LPAL13_350051600 ⚠
paraflagellar rod component, putative
— OG6
LPAL13_340011800 ⚠
vacuolar ATP synthase subunit d, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.