LPAL13_260023300

hypothetical protein, conserved
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102412 OG7: OG7_0006233 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_340018800 ⚠
threonyl-tRNA synthetase, putative
— Both
LPAL13_350006400 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LPAL13_070013700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LPAL13_330034700 ⚠
aminopeptidase, putative
— OG7
LPAL13_240027300 ⚠
tubulin folding cofactor D, putative
— Both
LPAL13_300011100 ⚠
hypothetical protein, conserved
— Both
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— Both
LPAL13_350079300 ⚠
beta-adaptin, putative
— Both
LPAL13_200060500 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LPAL13_030012100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LPAL13_080009200 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_200025800 ⚠
Uncharacterized conserved protein H4 (DUF2046
— Both
LPAL13_190010700 ⚠
C-terminal motor kinesin, putative
— OG6
LPAL13_340011800 ⚠
vacuolar ATP synthase subunit d, putative
— Both
LPAL13_000020300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_340016200 ⚠
NADH-dependent fumarate reductase, putative
— Both
LPAL13_200046600 ⚠
nucleolar protein family a, putative
— Both
LPAL13_340038500 ⚠
hypothetical protein, conserved
— Both
LPAL13_000018300 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_270020700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_120006800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_340048300 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_100006500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_340028700 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_330032900 ⚠
heat shock protein, putative
— OG7
LPAL13_200018100 ⚠
inositol 5-phosphatase-like protein
— OG7
LPAL13_200044700 ⚠
GRIP domain containing protein, putative
— Both
LPAL13_110013800 ⚠
adaptin-related protein-like protein
— OG7
LPAL13_350017400 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LPAL13_270020000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_150016700 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_240014000 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LPAL13_350062600 ⚠
adaptin, putative
— OG7
LPAL13_200042700 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_070014100 ⚠
FAD binding domain containing protein, putati
— Both
LPAL13_330008200 ⚠
heat shock protein 83-17
— +2 more Both
LPAL13_320014300 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LPAL13_200021900 ⚠
Zeta toxin, putative
— Both
LPAL13_080007000 ⚠
ubiquitin-activating enzyme-like protein
— Both
LPAL13_340013100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LPAL13_340016100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LPAL13_290005200 ⚠
transcription factor-like protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.