LPAL13_340016100

NADH-dependent fumarate reductase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_104311 OG7: OG7_0003099 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_110010200 ⚠
aminopeptidase, putative
— +2 more Both
LPAL13_280032200 ⚠
vacuolar ATP synthase subunit b, putative
— +2 more Both
LPAL13_300013500 ⚠
Armadillo/beta-catenin-like repeats, putative
— +2 more Both
LPAL13_330034700 ⚠
aminopeptidase, putative
— OG7
LPAL13_350006400 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LPAL13_280036000 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_260017100 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_280018900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_280036500 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_280035900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_000039200 ⚠
PA26 p53-induced protein (sestrin), putative
— Both
LPAL13_220010600 ⚠
Uncharacterised protein family UPF0066, putat
— Both
LPAL13_290008600 ⚠
hypothetical protein, conserved
— Both
LPAL13_150008200 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LPAL13_010005200 ⚠
DNA-damage inducible protein DDI1-like protei
— +2 more Both
LPAL13_340005000 ⚠
pyruvate kinase
— Both
LPAL13_240026100 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LPAL13_060009100 ⚠
glutamine synthetase, putative
— Both
LPAL13_130020200 ⚠
pyrroline-5-carboxylate reductase
— Both
LPAL13_000041400 ⚠
hypothetical protein, conserved
— Both
LPAL13_300017800 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— Both
LPAL13_350025900 ⚠
60S ribosomal protein L37a, putative
— Both
LPAL13_210025000 ⚠
60S ribosomal protein L37a, putative
— Both
LPAL13_350074100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— +2 more Both
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— +2 more Both
LPAL13_290010000 ⚠
NF-X1 type zinc finger containing protein, pu
— Both
LPAL13_220011100 ⚠
guide RNA associated protein, GAP2, putative
— Both
LPAL13_260023300 ⚠
hypothetical protein, conserved
— Both
LPAL13_100018300 ⚠
hypothetical protein, conserved
— Both
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— Both
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_340011800 ⚠
vacuolar ATP synthase subunit d, putative
— Both
LPAL13_350051600 ⚠
paraflagellar rod component, putative
— OG6
LPAL13_300011100 ⚠
hypothetical protein, conserved
— Both
LPAL13_130012600 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LPAL13_240027300 ⚠
tubulin folding cofactor D, putative
— +2 more Both
LPAL13_120007700 ⚠
ornithine decarboxylase, putative
— Both
LPAL13_350010200 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LPAL13_050013000 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LPAL13_290008000 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LPAL13_320028400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_330032900 ⚠
heat shock protein, putative
— +2 more OG7
LPAL13_320039800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_140015700 ⚠
protein kinase, putative
— OG7
LPAL13_350051800 ⚠
protein kinase-like protein
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_200042700 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LPAL13_140013200 ⚠
protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.