LPAL13_200030400

hypothetical protein, conserved
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102026 OG7: OG7_0007248 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_300018300
hypothetical protein, conserved
— Both
LPAL13_190015100 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
LPAL13_290006400 ⚠
DNA-directed RNA polymerase I-like protein
— Both
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_230006100 ⚠
Beige/BEACH domain containing protein, putati
— Both
LPAL13_200046800
coatomer alpha subunit, putative
— Both
LPAL13_350062600 ⚠
adaptin, putative
— Both
LPAL13_350029700 ⚠
hypothetical protein, conserved
— Both
LPAL13_350062300
glycosyl hydrolase, putative
— Both
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— Both
LPAL13_350028900
hypothetical protein, conserved
— Both
LPAL13_340027000
hypothetical protein, conserved
— Both
LPAL13_350029600 ⚠
hypothetical protein, conserved
— Both
LPAL13_340029400
hypothetical protein, conserved
— Both
LPAL13_200044900
hypothetical protein, conserved
— Both
LPAL13_350048600
hypothetical protein, conserved
— Both
LPAL13_200044700
GRIP domain containing protein, putative
— Both
LPAL13_350066900
hypothetical protein, conserved
— Both
LPAL13_200037700
zinc finger/Zinc finger domain containing pro
— Both
LPAL13_200048300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_310006600 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_350063900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_330027400 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_080012300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LPAL13_350040000 ⚠
Tubulin binding cofactor C, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_130020000 ⚠
chaperonin TCP20, putative
— +3 more OG7
LPAL13_100013700
hypothetical protein, conserved
— OG7
LPAL13_240029900 ⚠
cullin-like protein-like protein
— OG7
LPAL13_350031300 ⚠
Cullin protein neddylation domain containing
— OG7
LPAL13_350038900 ⚠
cullin-like protein
— OG7
LPAL13_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_160017100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_310031800 ⚠
RNA polymerase ii largest subunit
— OG7
LPAL13_330037000 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LPAL13_200007500 ⚠
RNA polymerase ii largest subunit
— OG7
LPAL13_230026800 ⚠
neutral sphingomyelinase activation associate
— OG7
LPAL13_200047300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LPAL13_270020000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_350079300 ⚠
beta-adaptin, putative
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_320021000 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LPAL13_200059700 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_340028700 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_110013800 ⚠
adaptin-related protein-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.