LPAL13_340045600

U5 snRNA-associated splicing factor
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101765 OG7: OG7_0006744 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_130008000 ⚠
ATP-dependent RNA helicase, putative
— Both
LPAL13_170015000 ⚠
ATP-dependent RNA helicase, putative
— Both
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LPAL13_320029200 ⚠
small nuclear ribonucleoprotein component-lik
— Both
LPAL13_320028200
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LPAL13_320032400
hypothetical protein, conserved
— Both
LPAL13_350052900
proteasome regulatory ATPase subunit
— OG6
LPAL13_320047900
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LPAL13_330041300
small nuclear ribonucleoprotein SmD2
— Both
LPAL13_340050700 ⚠
sm-f snRNP core complex protein, putative
— Both
LPAL13_160021400
Putative snoRNA binding domain containing pro
— Both
LPAL13_280035600 ⚠
receptor for activated C kinase 1
— OG7
LPAL13_350015800
40S ribosomal protein S10, putative
— Both
LPAL13_350070300
hypothetical protein, conserved
— Both
LPAL13_270021800
proteasome regulatory non-ATP-ase subunit 3,
— Both
LPAL13_110008800
spliceosomal U5 snRNP-specific protein, putat
— Both
LPAL13_160017400
hypothetical protein, conserved
— Both
LPAL13_000014800
proteasome regulatory non-ATPase subunit 6, p
— Both
LPAL13_310036200
acetyl-CoA carboxylase, putative
— Both
LPAL13_010005700
pre-mRNA processing factor 3 (PRP3)/Protein o
— Both
LPAL13_280035700 ⚠
receptor for activated C kinase 1
— OG7
LPAL13_000034700 ⚠
LSM domain containing protein, putative
— Both
LPAL13_300019800 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_260005100 ⚠
Lsm7p protein, putative
— OG7
LPAL13_200048200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LPAL13_320012700 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— OG7
LPAL13_180016300 ⚠
heat shock protein 110, putative
— OG7
LPAL13_340053700 ⚠
Hsp70 protein, putative
— OG7
LPAL13_010010200 ⚠
HSP70-like protein
— OG7
LPAL13_260013400 ⚠
heat shock 70 protein-like protein
— OG7
LPAL13_250023800 ⚠
elongation factor 2-like protein
— OG7
LPAL13_350006800 ⚠
elongation factor 2
— OG7
LPAL13_280036000 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_280038100
U5 snRNP-specific 40 kDa protein, putative
— Both
LPAL13_210017800
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LPAL13_220013000
small nuclear ribonucleoprotein, putative
— Both
LPAL13_010006300
hypothetical protein, conserved
— Both
LPAL13_150016300 ⚠
Cyclic nucleotide-binding domain containing p
— Both
LPAL13_320009000
19S proteasome non-atpase subunit 8
— Both
LPAL13_170013800
OSM3-like kinesin, putative
— OG6
LPAL13_120007000
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LPAL13_000013100
WD domain, G-beta repeat, putative
— Both
LPAL13_190017600
proteasome regulatory non-ATP-ase subunit 9,
— Both
LPAL13_290006200
proteasome regulatory non-ATPase subunit, put
— Both
LPAL13_150016400
protein kinase, putative
— OG6
LPAL13_070017500
proteasome regulatory non-ATP-ase subunit, pu
— Both
LPAL13_210012700
proteasome regulatory non-ATP-ase subunit 5,
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.