LPAL13_100013000

HEAT repeat, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_157992 OG7: OG7_0037640 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— Both
LPAL13_140009700 ⚠
cystathionine beta-lyase-like protein
— Both
LPAL13_210006900
CHAT domain containing protein, putative
— Both
LPAL13_210023800
hypothetical protein, conserved
— Both
LPAL13_000018300
phenylalanyl-tRNA synthetase, putative
— Both
LPAL13_210009500
vacuolar sorting-associated-like protein
— Both
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LPAL13_340040100 ⚠
zinc finger protein, putative
— Both
LPAL13_070015300
Domain of unknown function (DUF3437), putativ
— Both
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_340048700 ⚠
predicted zinc finger protein
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_310020100 ⚠
Leucine Rich repeat, putative
— Both
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_100006900 ⚠
MORN repeat, putative
— OG7
LPAL13_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_200042700 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LPAL13_320019700 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LPAL13_200051800 ⚠
developmentally regulated phosphoprotein-like
— OG7
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_190016400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_140017100 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_290026000
aspartyl aminopeptidase, putative
— Both
LPAL13_330026700
hypothetical protein, conserved
— Both
LPAL13_350074100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_310027100
ARM-like helical domain-containing protein
— Both
LPAL13_120007400
cysteinyl-tRNA synthetase, putative
— Both
LPAL13_270009000
hypothetical protein, conserved
— Both
LPAL13_180013400
5-oxoprolinase, putative
— Both
LPAL13_240010500
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LPAL13_160016500
hypothetical protein, conserved
— Both
LPAL13_280026800
p21-C-terminal region-binding protein, putati
— Both
LPAL13_290021700 ⚠
MORN repeat, putative
— Both
LPAL13_240005000 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
LPAL13_260023900
hypothetical protein, conserved
— Both
LPAL13_040011600
DENN (AEX-3) domain containing protein, putat
— Both
LPAL13_350032000
hypothetical protein, conserved
— Both
LPAL13_350036700
hypothetical protein, conserved
— Both
LPAL13_270020800
hypothetical protein, conserved
— Both
LPAL13_150009700
hypothetical protein, conserved
— Both
LPAL13_240027300
tubulin folding cofactor D, putative
— Both
LPAL13_090018500 ⚠
PPPDE putative peptidase domain containing pr
— Both
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_340037200 ⚠
cystathione gamma lyase, putative
— Both
LPAL13_170008900
Ring finger domain containing protein, putati
— Both
LPAL13_240012100 ⚠
PPPDE putative peptidase domain containing pr
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.